BDB742853
P-glycoprotein Mouse anti-Human, BUV395, Clone: 17F9, BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742853-Each-of-1 | In Stock | ₹ 49,306.00 |
BDB742853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,306.00
GST (18%): ₹ 8,875.08
Total Price: ₹ 58,181.08
Antigen
P-glycoprotein
Clone
17F9
Conjugate
Brilliant Ultraviolet 395
Gene Alias
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1
Immunogen
Human MDR1 Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b κ
Description
- The 17F9 monoclonal antibody specifically binds to the 170-180 kDa transmembrane glycoprotein (P-glycoprotein), a product of the multidrug resistance-1 (MDR1) gene
- This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many normal tissues, such as adrenal glands and endothelium, in the brain and skin
- P-glycoprotein is known to impart drug resistance to cells by pumping many anti-cancer drugs out of the cytoplasm
- 17F9 antibody is able to partially block the binding of UIC2 antibody (another MDR-specific monoclonal antibody)
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
- BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
- With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
- This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
Compare Similar Items
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Antigen: P-glycoprotein
Clone: 17F9
Conjugate: Brilliant Ultraviolet 395
Gene Alias: CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1
Immunogen: Human MDR1 Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
P-glycoprotein
Clone:
17F9
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1
Immunogen:
Human MDR1 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: TIM-3 (CD366)
Clone: 7D3
Conjugate: Brilliant Violet 605
Gene Alias: CD366, HAVCR2, TIM3, T cell immunoglobulin mucin-3, TIMD-3, KIM-3
Immunogen: Human TIM-3
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
TIM-3 (CD366)
Clone:
7D3
Conjugate:
Brilliant Violet 605
Gene Alias:
CD366, HAVCR2, TIM3, T cell immunoglobulin mucin-3, TIMD-3, KIM-3
Immunogen:
Human TIM-3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: H-2Kb
Clone: AF6-88.5
Conjugate: Brilliant Violet 510
Gene Alias: H2 class I histocompatibility alloantigen Kb
Immunogen: Mouse C57BL/6 Splenocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
H-2Kb
Clone:
AF6-88.5
Conjugate:
Brilliant Violet 510
Gene Alias:
H2 class I histocompatibility alloantigen Kb
Immunogen:
Mouse C57BL/6 Splenocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: H-2Kb
Clone: AF6-88.5
Conjugate: Brilliant Violet 786
Gene Alias: H2 class I histocompatibility alloantigen Kb
Immunogen: Mouse C57BL/6 Splenocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
H-2Kb
Clone:
AF6-88.5
Conjugate:
Brilliant Violet 786
Gene Alias:
H2 class I histocompatibility alloantigen Kb
Immunogen:
Mouse C57BL/6 Splenocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ