BDB742930
CD371 (Clec12A) Mouse anti-Human, Brilliant Violet 510, Clone: 50C1, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742930-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB742930 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
CD371 (Clec12A)
Clone
50C1
Conjugate
Brilliant Violet 510
Gene Alias
CD371, Clec12A, MICL, CLL-1, DCAL-2
Immunogen
Human CLEC12A Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The 50C1 monoclonal antibody specifically binds to human CD371 which is also known as Clec12A (C-type lectin domain family 12 member A), C-type lectin-like molecule 1 (CLL-1), myeloid inhibitory C-type lectin-like receptor (MICL), or dendritic cell-associated lectin 2 (DCAL-2)
- It is expressed on a variety of cells including monocytes, macrophages, dendritic cells, and granulocytes and perhaps some NK cells
- Clec12A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily
- It is a 30 kDa type II transmembrane glycoprotein that has one single C-type lectin-like domain and one cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM)
- Clec12A has similarity with theβ-glucan receptor (Dectin-1) and LOX-1 with high N-glycosylation
- There are at least five isoforms due to alternative transcript splicing
- Signaling through Clec12A can induce internalization of Clec12A, dendritic cell maturation and the production of cytokines including IL-12
- Clec12A may also serve as a negative regulator of activated leukocytes recruited to sites of inflammation The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
- BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
- BV510 is a polymer-based dye that is brighter than BD Horizon V500
- Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.
Compare Similar Items
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Antigen: CD371 (Clec12A)
Clone: 50C1
Conjugate: Brilliant Violet 510
Gene Alias: CD371, Clec12A, MICL, CLL-1, DCAL-2
Immunogen: Human CLEC12A Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD371 (Clec12A)
Clone:
50C1
Conjugate:
Brilliant Violet 510
Gene Alias:
CD371, Clec12A, MICL, CLL-1, DCAL-2
Immunogen:
Human CLEC12A Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD371 (Clec12A)
Clone: 50C1
Conjugate: Brilliant Violet 605
Gene Alias: CD371, Clec12A, MICL, CLL-1, DCAL-2
Immunogen: Human CLEC12A Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD371 (Clec12A)
Clone:
50C1
Conjugate:
Brilliant Violet 605
Gene Alias:
CD371, Clec12A, MICL, CLL-1, DCAL-2
Immunogen:
Human CLEC12A Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD59
Clone: p282 (H19)
Conjugate: Brilliant Violet 605
Gene Alias: HRF-20, MAC-inhibitory protein, MAC-IP, MACIF, MEM43, MIRL, Protectin, 1F5
Immunogen: Human Erythrocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD59
Clone:
p282 (H19)
Conjugate:
Brilliant Violet 605
Gene Alias:
HRF-20, MAC-inhibitory protein, MAC-IP, MACIF, MEM43, MIRL, Protectin, 1F5
Immunogen:
Human Erythrocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD59
Clone: p282 (H19)
Conjugate: Brilliant Violet 711
Gene Alias: HRF-20, MAC-inhibitory protein, MAC-IP, MACIF, MEM43, MIRL, Protectin, 1F5
Immunogen: Human Erythrocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD59
Clone:
p282 (H19)
Conjugate:
Brilliant Violet 711
Gene Alias:
HRF-20, MAC-inhibitory protein, MAC-IP, MACIF, MEM43, MIRL, Protectin, 1F5
Immunogen:
Human Erythrocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ