BDB742961
B7-H4 Mouse anti-Human, BUV395, Clone: MIH43, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742961-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB742961 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
B7-H4
Clone
MIH43
Conjugate
Brilliant Ultraviolet 395
Gene Alias
VTCN1, VCTN1, B7 family member, H4, B7H4, B7h.5, B7S1, B7X
Immunogen
Recombinant Human B7-H4 protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The MIH43 monoclonal antibody specifically binds to human B7-H4 (B7 family member, H4) that is encoded by the VTCN1 (V-set domain containing T cell activation inhibitor 1) gene
- B7-H4 is a type I membrane glycoprotein with a calculated molecular weight of 30.89 kDa
- It is also known as VCTN1, B7h.5, B7S1 (B7 superfamily member 1) or B7X
- B7-H4 is a newly discovered member of the B7 family of costimulatory proteins
- B7-H4 is not constitutively expressed on peripheral tissues
- Its expression can be induced on macrophages, dendritic cells, B cells and T cells
- By binding to its putative receptor, the function of B7-H4 was initially reported to be a negative regulator of T cell activation, proliferation and differentiation related to cytokine production and cytotoxic effector cell functions
- B7-H4 is reportedly overexpressed in a variety tumors
- B7-H4 expression by tumor macrophages appears to play a role in suppression antigen-specific T cell mediated immunity
- Recent studies indicate that B7-H4 can also be a positive regulator of T cell responses
- B7-H4 can be involved innate immunity as well, eg, by inhibiting neutrophil expansion
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
- BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
- With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
- This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
Compare Similar Items
Show Difference
Antigen: B7-H4
Clone: MIH43
Conjugate: Brilliant Ultraviolet 395
Gene Alias: VTCN1, VCTN1, B7 family member, H4, B7H4, B7h.5, B7S1, B7X
Immunogen: Recombinant Human B7-H4 protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
B7-H4
Clone:
MIH43
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
VTCN1, VCTN1, B7 family member, H4, B7H4, B7h.5, B7S1, B7X
Immunogen:
Recombinant Human B7-H4 protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD53
Clone: HI29
Conjugate: Brilliant Violet 421
Gene Alias: tetraspanin-25, TSPAN25, tspan-25, MOX44
Immunogen: Human Peripheral Blood Mononuclear Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD53
Clone:
HI29
Conjugate:
Brilliant Violet 421
Gene Alias:
tetraspanin-25, TSPAN25, tspan-25, MOX44
Immunogen:
Human Peripheral Blood Mononuclear Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD53
Clone: HI29
Conjugate: Brilliant Violet 786
Gene Alias: tetraspanin-25, TSPAN25, tspan-25, MOX44
Immunogen: Human Peripheral Blood Mononuclear Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD53
Clone:
HI29
Conjugate:
Brilliant Violet 786
Gene Alias:
tetraspanin-25, TSPAN25, tspan-25, MOX44
Immunogen:
Human Peripheral Blood Mononuclear Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD53
Clone: HI29
Conjugate: Brilliant Ultraviolet 395
Gene Alias: tetraspanin-25, TSPAN25, tspan-25, MOX44
Immunogen: Human Peripheral Blood Mononuclear Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD53
Clone:
HI29
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
tetraspanin-25, TSPAN25, tspan-25, MOX44
Immunogen:
Human Peripheral Blood Mononuclear Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ