BDB743018

ROR1 Mouse anti-Human, BUV395, Clone: 4A5, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743018-Each-of-1 In Stock ₹ 47,400.24

BDB743018 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

ROR1

Clone

4A5

Conjugate

Brilliant Ultraviolet 395

Gene Alias

Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1

Immunogen

Human ROR1 cDNA

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Description

  • The 4A5 monoclonal antibody binds to the glycosylated type I membrane protein ROR1 (Receptor-tyrosine-kinase-like Orphan Receptor 1)
  • The ROR1 and ROR2 related proteins are highly conserved evolutionarily and are primarily expressed during embryogenesis
  • ROR1 is not expressed on normal peripheral blood lymphocytes
  • ROR1 is similar to tropomyosin receptor kinase (Trk family) neurotropic receptors and shares a cysteine-rich domain with Frizzled receptors for Wnt-family signaling proteins, which are involved in the regulation of embryogenesis and carcinogenesis
  • Furthermore, there is mounting evidence that aberrant ROR1 expression contributes to human malignancy
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

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Antigen:
ROR1

Clone:
4A5

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1

Immunogen:
Human ROR1 cDNA

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

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Antigen:
Vβ4 T-Cell Receptor

Clone:
KT4

Conjugate:
Brilliant Violet 510

Gene Alias:
TCR V beta 4, TCR Vβ4

Immunogen:
KT4 B10.D2 mouse T-cell clone I3

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
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Purification Method:
Affinity Purified

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RUO

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Mouse

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IgG2b κ

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TCR V beta 4, TCR Vβ4

Immunogen:
KT4 B10.D2 mouse T-cell clone I3

Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

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Clone:
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Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
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Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

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