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BDB743130

Neuropilin-1 (CD304) Mouse anti-Human, Brilliant Violet 605, Clone: U21-1283, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743130-Each-of-1 In Stock ₹ 47,400.24

BDB743130 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

Neuropilin-1 (CD304)

Clone

U21-1283

Conjugate

Brilliant Violet 605

Gene Alias

Neuropilin, NRP, NP1, Blood dendritic cell antigen 4, BDCA-4, VEGF165R

Immunogen

Recombinant Human Neuropilin-1

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Description

  • The U21-1283 monoclonal antibody specifically recognizes Neuropilin-1 (NRP1), also known as CD304, Blood dendritic cell antigen 4 (BDCA4), and Vascular endothelial cell growth factor 165 receptor (VEGF165R)
  • CD304 is a type I transmembrane glycoprotein involved in the development of the nervous and cardiovascular systems
  • It mediates the interaction, growth, survival, and migration of a variety of normal and tumor cells
  • CD304 is expressed on neurons, thymocytes, regulatory T cells, a subset of T follicular helper cells, dendritic cells, endothelial cells, and certain tumor cells
  • Neuropilin-1 has a very short cytoplasmic domain and interacts with various coreceptors to form ligand-binding, signal-transducing receptor complexes
  • CD304 complexes with Plexin-A family members to bind chemorepellent Class 3 Semaphorins and guide neuronal axon growth
  • It also functions as a coreceptor with VEGFR2/CD309 to stimulate angiogenesis in response to VEGF165
  • CD304 mediates the interactions between some T cells and dendritic cells
  • This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407nm and Em Max of 602nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20nm filter set
  • BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605nm
  • Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers
  • BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser
  • BV605 is a tandem fluorochrome that combines BD Horizon BV421 and Cy™3.5
  • These conjugates are very bright, exhibiting similar brightness to equivalent PE conjugates
  • Due to the excitation of Cy3.5 by the green (532nm) and yellow-green (561nm) lasers, there will be significant spillover of the BD Horizon BV605 signal into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers.

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BD Biosciences

BDB743130

--

Antigen:
Neuropilin-1 (CD304)
Clone:
U21-1283
Conjugate:
Brilliant Violet 605
Gene Alias:
Neuropilin, NRP, NP1, Blood dendritic cell antigen 4, BDCA-4, VEGF165R
Immunogen:
Recombinant Human Neuropilin-1
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743132

--

Antigen:
Neuropilin-1 (CD304)
Clone:
U21-1283
Conjugate:
Brilliant Violet 786
Gene Alias:
Neuropilin, NRP, NP1, Blood dendritic cell antigen 4, BDCA-4, VEGF165R
Immunogen:
Recombinant Human Neuropilin-1
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743134

--

Antigen:
CD281 (TLR1)
Clone:
TR23
Conjugate:
Brilliant Violet 510
Gene Alias:
Cd281; Tlr1; Toll-like receptor 1; TIL; Toll/interleukin-1 receptor-like
Immunogen:
Mouse TLR1 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ

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BD Biosciences

BDB743141

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Antigen:
CD115 (CSF-1R)
Clone:
9-4D2-1E4 (also known as 9-4D2)
Conjugate:
Brilliant Violet 510
Gene Alias:
CSF-1R, CSF1R, C-FMS, FMS, FIM2, M-CSF-R
Immunogen:
Human CD115 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ