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BDB743197

CD93 Mouse anti-Human, Brilliant Violet 605, Clone: R139, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743197-Each-of-1 In Stock ₹ 47,614.14

BDB743197 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD93

Clone

R139

Conjugate

Brilliant Violet 605

Gene Alias

C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1

Immunogen

Clq-CLF-binding proteins

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Description

  • The R139 monoclonal antibody specifically binds to CD93 which is also known as Complement component C1q receptor (C1qR), C1q receptor 1 (C1qR1), or Matrix-remodeling-associated protein 4 (MXRA4)
  • The immunogen used to generate the R139 hybridoma was a preparation of CD93 protein
  • Human CD93 is a transmembrane glycoprotein that is highly expressed on monocytes, macrophages, granulocytes, and endothelial cells but not on T and B lymphocytes
  • CD93 is also known as the C1q/MBL/SPA Receptor as it binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA (Pulmonary Surfactant Protein A)
  • Human C1qRp is involved in the C1q-mediated enhancement of phagocytosis
  • R139 is suitable to detect CD93 expression on cells of myeloid lineage by flow cytometry, and CD93 in cellular lysates by Western blotting or immunoprecipitation
  • In addition, R139 reportedly neutralizes C1q-mediated enhancement of phagocytosis
  • CD93 has also been reported to define a human stem cell population with hematopoietic and hepatic potential
  • This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407nm and Em Max of 602nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20nm filter set
  • BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605nm
  • Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers
  • BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser
  • BV605 is a tandem fluorochrome that combines BD Horizon BV421 and Cy™3.5
  • These conjugates are very bright, exhibiting similar brightness to equivalent PE conjugates
  • Due to the excitation of Cy3.5 by the green (532nm) and yellow-green (561nm) lasers, there will be significant spillover of the BD Horizon BV605 signal into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers.

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BD Biosciences

BDB743197

--

Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 605
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743198

--

Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 650
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

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BD Biosciences

BDB743199

--

Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 786
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

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BD Biosciences

BDB743201

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Antigen:
CD49b
Clone:
12F1
Conjugate:
Brilliant Violet 421
Gene Alias:
Integrin α2 chain; ITGA2; VLA-2 alpha; Platelet GPIa; Collagen receptor; BR
Immunogen:
Human PBMC and Platelets
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon Brilliant Violet 421 under optimal conditions that minimize unconjugated dye and antibody.
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ