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BDB743210

CD62L Mouse anti-Human, Brilliant Violet 650, Clone: SK11 (also known as Anti-Leu-8), BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743210-Each-of-1 In Stock ₹ 47,614.14

BDB743210 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD62L

Clone

SK11 (also known as Anti-Leu-8)

Conjugate

Brilliant Violet 650

Gene Alias

L-selectin, LECAM-1, SELL, LNHR, LSEL, LAM-1, LEU8, PLNHR, TQ-1, MEL-14

Immunogen

Human Peripheral Blood T Lymphocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Description

  • The SK11 monoclonal antibody specifically binds to CD62L which is also known as, L-selectin, Leukocyte-endothelial cell adhesion molecule 1 (LECAM1/LECAM-1), Leukocyte adhesion molecule 1 (LAM1/LAM-1), Lymph node homing receptor (LNHR), Leu-8, or TQ1
  • CD62L is an ñ80 kDa type I transmembrane glycoprotein that belongs to the Selectin/LECAM family
  • CD62L is differentially expressed on T cells, B cells, monocytes, granulocytes, and a subset of NK cells
  • The CD62L molecule is the human homolog of the mouse lymph node homing receptor, MEL-14
  • CD62L plays a role in leucocyte binding to inflamed endothelium and extravasation, as well as mediating lymphocyte homing into peripheral lymphoid tissues through high endothelial postcapillary venules
  • Soluble CD62L can result from the proteolytic cleavage of cell surface CD62L during cellular activation or inflammation
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

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BD Biosciences

BDB743210

--

Antigen:
CD62L
Clone:
SK11 (also known as Anti-Leu-8)
Conjugate:
Brilliant Violet 650
Gene Alias:
L-selectin, LECAM-1, SELL, LNHR, LSEL, LAM-1, LEU8, PLNHR, TQ-1, MEL-14
Immunogen:
Human Peripheral Blood T Lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ

Img

BD Biosciences

BDB743213

--

Antigen:
CD86
Clone:
24F
Conjugate:
Brilliant Violet 605
Gene Alias:
Cd86, B7-2
Immunogen:
HTLV-1-transformed rat T-cell line Lewis-S1
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

Img

BD Biosciences

BDB743214

--

Antigen:
CD86
Clone:
24F
Conjugate:
Brilliant Violet 650
Gene Alias:
Cd86, B7-2
Immunogen:
HTLV-1-transformed rat T-cell line Lewis-S1
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

Img

BD Biosciences

BDB743215

--

Antigen:
CD86
Clone:
24F
Conjugate:
Brilliant Violet 711
Gene Alias:
Cd86, B7-2
Immunogen:
HTLV-1-transformed rat T-cell line Lewis-S1
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ