Home Products Antibodies Primary Antibodies BDB743242
BDB743242

Vγ 3 TCR Hamster anti-Mouse, Brilliant Violet 711, Clone: 536, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743242-Each-of-1 In Stock ₹ 34,052.88

BDB743242 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

Vγ 3 TCR

Clone

536

Conjugate

Brilliant Violet 711

Gene Alias

TCR Vγ3, TCR V gamma 3, TCR Vg3

Immunogen

AKR mouse dendritic epidermal cell clone 7-17

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Syrian Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Description

  • The 536 monoclonal antibody specifically recognizes Vγ3† T-cell Receptor (TCR)-bearing T lymphocytes, which are the predominantγδTCR-bearing cells in the early fetal thymus and the adult epidermis of euthymic mice
  • The first T cells to mature in the embryonic thymus express the Vγ3 and Vδ1 TCR chains, and their development is dependent upon IL-7
  • There is evidence that the Vγ3 TCR-bearing fetal thymocytes are the precursors of the majority of dendritic epidermal T cells (DEC), which may be replenished in the adult by proliferation in situ /rather than by seeding from primary lymphoid organs
  • Although the Vγ3 TCR is almost exclusively found in the DEC population, it has been shown that the homing of DEC to the epidermis does not require expression of the Vγ3 gene segment
  • Vγ3 TCR-bearing dermal dendritic cells have also been described
  • Vγ3 TCR has also been found on a subset of T lymphocytes in the lactating mammary gland and at the site of antigenic challenge in contact-sensitized mice
  • Plate-bound 536 antibody activates Vγ3 TCR-bearing T cells, and Fab fragments of mAb 536 block in vitro /stimulation of DEC by keratinocytes
  • The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
  • BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
  • This dye offers a very bright choice for the violet laser
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB743242

--

Antigen:
Vγ 3 TCR
Clone:
536
Conjugate:
Brilliant Violet 711
Gene Alias:
TCR Vγ3, TCR V gamma 3, TCR Vg3
Immunogen:
AKR mouse dendritic epidermal cell clone 7-17
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Syrian Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

Img

BD Biosciences

BDB743243

--

Antigen:
Vγ 3 TCR
Clone:
536
Conjugate:
Brilliant Violet 786
Gene Alias:
TCR Vγ3, TCR V gamma 3, TCR Vg3
Immunogen:
AKR mouse dendritic epidermal cell clone 7-17
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Syrian Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

Img

BD Biosciences

BDB743244

--

Antigen:
Vγ 3 TCR
Clone:
536
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
TCR Vγ3, TCR V gamma 3, TCR Vg3
Immunogen:
AKR mouse dendritic epidermal cell clone 7-17
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Syrian Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ

Img

BD Biosciences

BDB743253

--

Antigen:
CD155
Clone:
3F1
Conjugate:
Brilliant Violet 510
Gene Alias:
Poliovirus receptor, Pvr, Tumor-associated antigen 1, Taa1, Tage4, HVED
Immunogen:
Mouse CD155 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ