BDB743308

CD71 Mouse anti-Human, BUV395, Clone: M-A712, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743308-Each-of-1 In Stock ₹ 46,287.96

BDB743308 - Each of 1

₹ 46,287.96

In Stock

Quantity

1

Base Price: ₹ 46,287.96

GST (18%): ₹ 8,331.833

Total Price: ₹ 54,619.793

Antigen

CD71

Clone

M-A712

Conjugate

Brilliant Ultraviolet 395

Gene Alias

TFR, TFRC, Trfr, TfR1, Transferrin receptor protein 1

Immunogen

T-CLL and Jurkat Cells

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Description

  • The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR)
  • This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers
  • CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells
  • CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens
  • Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin
  • After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

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Antigen:
CD71

Clone:
M-A712

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
TFR, TFRC, Trfr, TfR1, Transferrin receptor protein 1

Immunogen:
T-CLL and Jurkat Cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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Primary or Secondary:
Primary

Content And Storage:
Refrigerate (2 to 8°C)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

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Host Species:
Mouse

Purification Method:
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IgG2a κ

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Mouse

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IgG2a κ

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Primary or Secondary:
Primary

Content And Storage:
Refrigerate (2 to 8°C)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

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Host Species:
Mouse

Purification Method:
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Regulatory Status:
RUO

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