BDB743426
CD23 Mouse anti-Human, Brilliant Violet 421, Clone: EBVCS-5 (also known as EBVCS 5), BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743426-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB743426 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
CD23
Clone
EBVCS-5 (also known as EBVCS 5)
Conjugate
Brilliant Violet 421
Gene Alias
CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen
Epstein-Barr Virus Transformed Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The EBVCS-5 antibody specifically binds to human CD23, the low affinity receptor for human IgE (Fc epsilon RII orFcεRII), which is also known as C-type lectin domain family 4 member J (CLEC4J)
- CD23 is expressed as a ñ45 kDa type II membrane glycoprotein that is present at low density on most normal B lymphocytes and at higher levels on activated B lymphocytes, Epstein-Barr virus (EBV)-transformed lymphoblasts, chronic lymphocytic leukemia (CLL) cells of B-lymphocyte origin, and tonsillar B lymphocytes
- CD23 expression is induced on B cells by interleukin-4 (IL-4) and is lost after isotype switching to IgA, IgG, or IgE
- The CD23 antigen is not present on immature bone marrow B lymphocytes or on T lymphocytes
- CD23 may also be differentially expressed on monocytes, macrophages, eosinophils, platelets, dendritic cells, and Langerhans cells
- CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils
- Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23
- Larger fragments of sCD23 (eg, 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (ie, ≤ 12 kDa) do not
- Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types
- The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
- BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
- BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
- Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
- Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
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Show Difference
Antigen: CD23
Clone: EBVCS-5 (also known as EBVCS 5)
Conjugate: Brilliant Violet 421
Gene Alias: CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen: Epstein-Barr Virus Transformed Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD23
Clone:
EBVCS-5 (also known as EBVCS 5)
Conjugate:
Brilliant Violet 421
Gene Alias:
CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen:
Epstein-Barr Virus Transformed Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD23
Clone: EBVCS-5 (also known as EBVCS 5)
Conjugate: Brilliant Violet 510
Gene Alias: CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen: Epstein-Barr Virus Transformed Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD23
Clone:
EBVCS-5 (also known as EBVCS 5)
Conjugate:
Brilliant Violet 510
Gene Alias:
CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen:
Epstein-Barr Virus Transformed Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD23
Clone: EBVCS-5 (also known as EBVCS 5)
Conjugate: Brilliant Violet 605
Gene Alias: CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen: Epstein-Barr Virus Transformed Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD23
Clone:
EBVCS-5 (also known as EBVCS 5)
Conjugate:
Brilliant Violet 605
Gene Alias:
CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen:
Epstein-Barr Virus Transformed Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD23
Clone: EBVCS-5 (also known as EBVCS 5)
Conjugate: Brilliant Violet 650
Gene Alias: CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen: Epstein-Barr Virus Transformed Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD23
Clone:
EBVCS-5 (also known as EBVCS 5)
Conjugate:
Brilliant Violet 650
Gene Alias:
CD23A, Fc-epsilon-RII, FCER2, FCE2, IGEBF, BLAST-2, CLEC4J, Leu-20
Immunogen:
Epstein-Barr Virus Transformed Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ