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BDB743574

CD268 (BAFF Receptor) Mouse anti-Human, Brilliant Violet 786, Clone: 11C1, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743574-Each-of-1 In Stock ₹ 47,400.24

BDB743574 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD268 (BAFF Receptor)

Clone

11C1

Conjugate

Brilliant Violet 786

Gene Alias

BAFF Receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C

Immunogen

Human BAFF-R Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 11C1 monoclonal antibody recognizes CD268 which is also known as the B cell activating factor receptor (BAFF-R)
  • CD268 is a type III transmembrane protein of approximately 184 residues
  • BAFF-R is one of the receptors for B-cell activating factor (BAFF), a member of the TNF family of proteins
  • BAFF is a key regulator for B cell differentiation and critical in regulating survival and activation of peripheral B cell populations
  • Experiments in the mouse model show that interaction of BAFF with BAFF-R promotes NF-κB activity
  • Overexpression of BAFF results in an expanded B cell compartment and autoimmunity in mice
  • Mice injected with BAFF-neutralizing-Fc (BAFF-R-Fc) protein showed reduced NF-κB activation, blocking BAFF-induced B cell proliferation
  • Reports suggest that the BAFF-BAFF-R interaction may lead to a better understanding of autoimmune disorders
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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BD Biosciences

BDB743574

--

Antigen:
CD268 (BAFF Receptor)
Clone:
11C1
Conjugate:
Brilliant Violet 786
Gene Alias:
BAFF Receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C
Immunogen:
Human BAFF-R Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

Img

BD Biosciences

BDB743576

--

Antigen:
CD110
Clone:
1.6.1
Conjugate:
Brilliant Violet 421
Gene Alias:
C-MPL, MPL, MPLV, TPOR, Thrombopoietin receptor
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

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BD Biosciences

BDB743579

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Antigen:
CD110
Clone:
1.6.1
Conjugate:
Brilliant Violet 650
Gene Alias:
C-MPL, MPL, MPLV, TPOR, Thrombopoietin receptor
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

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BD Biosciences

BDB743580

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Antigen:
CD110
Clone:
1.6.1
Conjugate:
Brilliant Violet 711
Gene Alias:
C-MPL, MPL, MPLV, TPOR, Thrombopoietin receptor
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ