BDB743641
CD115 (CSF-1R) Rat anti-Mouse, Brilliant Violet 650, Clone: T38-320, BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743641-Each-of-1 | In Stock | ₹ 34,224.00 |
BDB743641 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
CD115 (CSF-1R)
Clone
T38-320
Conjugate
Brilliant Violet 650
Gene Alias
M-CSFR, M-CSF-R, CSF-1 Receptor, CSF-1R, Csf1r, Csfmr, Fms, c-Fms, Fim-2
Immunogen
Mouse CD115 Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 κ
Description
- The T38-320 monoclonal antibody specifically binds to CD115 which is also known as Colony stimulating factor 1 Receptor (CSF-1R) or Macrophage colony-stimulating factor 1 receptor (M-CSFR)
- This type I transmembrane glycoprotein is a receptor tyrosine kinase (RTK) that belongs to the Ig superfamily
- It is expressed on a variety of cells including those committed to the mononuclear phagocyte lineage, such as, monocytes, macrophages, and osteoclasts
- CSF-1 binds to and signals through CSF-1R homodimers which undergo tyrosine autophosphorylation and transduce downstream signaling pathways resulting in cytoskeletal reorganization and gene expression
- CSF-1R activation stimulates the proliferation, differentiation, and survival of cells within the mononuclear phagocyte system
- Interleukin-34 (IL-34) is another ligand for CD115 that can induce similar, as well as, some different biological responses by CD115-positive target cells
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
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Antigen: CD115 (CSF-1R)
Clone: T38-320
Conjugate: Brilliant Violet 650
Gene Alias: M-CSFR, M-CSF-R, CSF-1 Receptor, CSF-1R, Csf1r, Csfmr, Fms, c-Fms, Fim-2
Immunogen: Mouse CD115 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD115 (CSF-1R)
Clone:
T38-320
Conjugate:
Brilliant Violet 650
Gene Alias:
M-CSFR, M-CSF-R, CSF-1 Receptor, CSF-1R, Csf1r, Csfmr, Fms, c-Fms, Fim-2
Immunogen:
Mouse CD115 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: CD115 (CSF-1R)
Clone: T38-320
Conjugate: Brilliant Ultraviolet 395
Gene Alias: M-CSFR, M-CSF-R, CSF-1 Receptor, CSF-1R, Csf1r, Csfmr, Fms, c-Fms, Fim-2
Immunogen: Mouse CD115 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD115 (CSF-1R)
Clone:
T38-320
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
M-CSFR, M-CSF-R, CSF-1 Receptor, CSF-1R, Csf1r, Csfmr, Fms, c-Fms, Fim-2
Immunogen:
Mouse CD115 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: CD103
Clone: Ber-ACT8
Conjugate: Brilliant Violet 786
Gene Alias: ITGAE, Integrin alpha-E, ITAE, HML-1 antigen, Mucosal lymphocyte 1, HUMINAE
Immunogen: Human MAPS16 T Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD103
Clone:
Ber-ACT8
Conjugate:
Brilliant Violet 786
Gene Alias:
ITGAE, Integrin alpha-E, ITAE, HML-1 antigen, Mucosal lymphocyte 1, HUMINAE
Immunogen:
Human MAPS16 T Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD300c
Clone: TX45
Conjugate: Brilliant Violet 421
Gene Alias: __
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Refrigerate (2 to 8°C)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD300c
Clone:
TX45
Conjugate:
Brilliant Violet 421
Gene Alias:
__
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Refrigerate (2 to 8°C)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ