BDB743819
IL-17 Receptor B Rat anti-Mouse, Brilliant Violet 711, Clone: 6B7, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743819-Each-of-1 | In Stock | ₹ 34,224.00 |
BDB743819 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
IL-17 Receptor B
Clone
6B7
Conjugate
Brilliant Violet 711
Gene Alias
IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen
Mouse IL-17 Receptor B Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 κ
Related Products
Description
- The 6B7 monoclonal antibody specifically binds to IL-17 Receptor B (IL-17RB), which is a single-pass type I transmembrane protein and a component of the heterodimeric receptor for IL-25 (also known as IL-17E)
- Several components of the IL-17RB signaling mechanism have been identified, including ACT1, TRAF4, SMURF2, DAZAP2, and STAT5
- The cytoplasmic tails of both of the IL-25 Receptor components, IL-17RA and IL-17RB, and ACT1 contain the SEFIR (similar expression to fibroblast growth factor genes and IL-17R) domain that is essential for IL-25R-mediated signaling
- Signaling through IL-17RB mediates Th2 immune responses and is responsible for pathogenesis in a murine model for asthma
- IL-17RB is found on subsets of iNKT cells, Th2 cells, some myeloid cells in solid organs, and type 2 innate lymphoid cells (ILC2) in lung, peritoneum, mesenteric lymph nodes and bone marrow
- The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
- BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
- This dye offers a very bright choice for the violet laser
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.
Compare Similar Items
Show Difference
Antigen: IL-17 Receptor B
Clone: 6B7
Conjugate: Brilliant Violet 711
Gene Alias: IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen: Mouse IL-17 Receptor B Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
IL-17 Receptor B
Clone:
6B7
Conjugate:
Brilliant Violet 711
Gene Alias:
IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen:
Mouse IL-17 Receptor B Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: IL-17 Receptor B
Clone: 6B7
Conjugate: Brilliant Violet 786
Gene Alias: IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen: Mouse IL-17 Receptor B Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
IL-17 Receptor B
Clone:
6B7
Conjugate:
Brilliant Violet 786
Gene Alias:
IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen:
Mouse IL-17 Receptor B Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: IL-17 Receptor B
Clone: 6B7
Conjugate: Brilliant Ultraviolet 395
Gene Alias: IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen: Mouse IL-17 Receptor B Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
IL-17 Receptor B
Clone:
6B7
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
IL-17RB, IL-17B receptor, Il17rb, Evi27, Il17rb, IL-17ER, IL17RH1, IL-17Rh1
Immunogen:
Mouse IL-17 Receptor B Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: HVEM (CD270)
Clone: CW10
Conjugate: Brilliant Violet 510
Gene Alias: TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen: Human Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
HVEM (CD270)
Clone:
CW10
Conjugate:
Brilliant Violet 510
Gene Alias:
TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen:
Human Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ