BDB744265

Ly-49H Mouse anti-Mouse, Brilliant Violet 786, Clone: 3D10, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB744265-Each-of-1 In Stock ₹ 34,052.88

BDB744265 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

Ly-49H

Clone

3D10

Conjugate

Brilliant Violet 786

Gene Alias

Ly49h, Lymphocyte antigen 49H, Klra8, Cmv1, Cmv-1

Immunogen

Mouse Ly-49A/H Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

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Description

  • The 3D10 monoclonal antibody specifically binds to mouse Lymphocyte antigen 49H (Ly-49H; also known as Klra8 or Killer cell lectin-like receptor 8)
  • The 3D10 antibody does not crossreact with related molecules such as Ly-49A, C, D or G2
  • Ly-49H is a type II transmembrane protein and a member of the Ly-49 C-type lectin multigene family of receptors expressed by NK cells
  • Cell surface Ly-49H is expressed by a subset of NK cells but not by NKT cells
  • Ly-49H is expressed by C57BL/6 and NWNA but not by BALB/c or DBA/2 mouse NK cells
  • Cell surface Ly-49H presents as a ñ110 kDa disfulfide-linked homodimer and associates with signaling subunits such as DAP10 and DAP12 for optimal transduction of intracellular activation signals
  • Crosslinking of Ly-49H with the 3D10 antibody reportedly induces NK cell cytotoxicity and cytokine production
  • Ly-49H recognizes the mouse cytomegalovirus m157 glycoprotein that is expressed by infected cells and is required for protection against cytomegalovirus infection
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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Show Difference

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BD Biosciences

BDB744265

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Antigen:
Ly-49H

Clone:
3D10

Conjugate:
Brilliant Violet 786

Gene Alias:
Ly49h, Lymphocyte antigen 49H, Klra8, Cmv1, Cmv-1

Immunogen:
Mouse Ly-49A/H Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Img

BD Biosciences

BDB744268

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Antigen:
CD44

Clone:
515

Conjugate:
Brilliant Violet 510

Gene Alias:
Pgp-1, CSPG8, ECMR-III, Epican, H-CAM, HCELL, Hermes, HUTCH-1

Immunogen:
Human EBV-transformed Arent B Lymphoblastoid Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

BDB744269

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Antigen:
CD44

Clone:
515

Conjugate:
Brilliant Violet 605

Gene Alias:
Pgp-1, CSPG8, ECMR-III, Epican, H-CAM, HCELL, Hermes, HUTCH-1

Immunogen:
Human EBV-transformed Arent B Lymphoblastoid Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB744271

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Antigen:
CD44

Clone:
515

Conjugate:
Brilliant Violet 711

Gene Alias:
Pgp-1, CSPG8, ECMR-III, Epican, H-CAM, HCELL, Hermes, HUTCH-1

Immunogen:
Human EBV-transformed Arent B Lymphoblastoid Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ