BDB744562
LAIR-1 (CD305) Mouse anti-Human, Brilliant Violet 786, Clone: DX26, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB744562-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB744562 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
LAIR-1 (CD305)
Clone
DX26
Conjugate
Brilliant Violet 786
Gene Alias
CD305, LAIR1, hLAIR1, Leukocyte-associated Ig-like receptor 1
Immunogen
Human NK Cell Clone
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The DX26 monoclonal antibody specifically binds to Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1/ hLAIR1/Leukocyte-associated Ig-like receptor 1) that is encoded by LAIR1, /and also known as, CD305
- LAIR-1 is a ñ32 kDa type I transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail containing two immune receptor tyrosine-based inhibitory (ITIM) motifs
- LAIR-1 is expressed on T cells, B cells, NK cells, monocytes, and dendritic cells
- LAIR-1 recruits SHP-1 and SHP-2 tyrosine phosphatases upon activation
- Crosslinking of the LAIR-1 expressed on T cells or NK cells can result in strong inhibition of cell-mediated cytotoxicity
- Although it is structurally related to human killer cell inhibitory receptors, LAIR-1 does not appear to recognize MHC class I molecules and thus represents a novel MHC class I-independent mechanism of NK cell regulation
- The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
- BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
- BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
- BV786 offers a bright choice for the 6th detector off the violet laser.
Compare Similar Items
Show Difference
Antigen: LAIR-1 (CD305)
Clone: DX26
Conjugate: Brilliant Violet 786
Gene Alias: CD305, LAIR1, hLAIR1, Leukocyte-associated Ig-like receptor 1
Immunogen: Human NK Cell Clone
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
LAIR-1 (CD305)
Clone:
DX26
Conjugate:
Brilliant Violet 786
Gene Alias:
CD305, LAIR1, hLAIR1, Leukocyte-associated Ig-like receptor 1
Immunogen:
Human NK Cell Clone
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: LAIR-1 (CD305)
Clone: DX26
Conjugate: Brilliant Ultraviolet 395
Gene Alias: CD305, LAIR1, hLAIR1, Leukocyte-associated Ig-like receptor 1
Immunogen: Human NK Cell Clone
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
LAIR-1 (CD305)
Clone:
DX26
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
CD305, LAIR1, hLAIR1, Leukocyte-associated Ig-like receptor 1
Immunogen:
Human NK Cell Clone
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD108
Clone: KS-2
Conjugate: Brilliant Violet 421
Gene Alias: JMH, SEM7A, Sema K1, Sema L, John-Milton-Hargen human blood group Ag
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD108
Clone:
KS-2
Conjugate:
Brilliant Violet 421
Gene Alias:
JMH, SEM7A, Sema K1, Sema L, John-Milton-Hargen human blood group Ag
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD108
Clone: KS-2
Conjugate: Brilliant Violet 650
Gene Alias: JMH, SEM7A, Sema K1, Sema L, John-Milton-Hargen human blood group Ag
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD108
Clone:
KS-2
Conjugate:
Brilliant Violet 650
Gene Alias:
JMH, SEM7A, Sema K1, Sema L, John-Milton-Hargen human blood group Ag
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ