BD AbSeq™ CD38 Rat, anti-Mouse, Oligo, Clone: 90/CD38, BD AbSeq™

Description

• The 90 monoclonal antibody specifically binds to CD38, a 42 kDa transmembrane glycoprotein on immature and mature, resting and activated, B lymphocytes
• In contrast to humans, CD38 expression is down-regulated on mouse germinal center B cells and plasma cells
• CD38 is also expressed on a subpopulation of thymic and peripheral T cells, NK cells, and splenic macrophages
• Furthermore, CD38 has been detected on bone marrow-derived hematopoietic stem cells
• The CD38 molecule is reported to exhibit both cyclase and hydrolase activities and plays a role in lymphocyte activation
• CD31, both human and mouse, is reported to be a ligand for human CD38.