CC12100UG

MilliporeSigma™ anti-Cyclin D1 Clone: DCS-6,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 CC12100UG-Each-of-1 In Stock ₹ 36,249.21

CC12100UG - Each of 1

₹ 36,249.21

In Stock

Quantity

1

Base Price: ₹ 36,249.21

GST (18%): ₹ 6,524.858

Total Price: ₹ 42,774.068

Antigen

Cyclin D1

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Purified

Applications

Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization

Clone

DCS-6

Formulation

In 50mM sodium phosphate buffer, 0.2% gelatin.

Immunogen

recombinant human cyclin D1

Regulatory Status

RUO

Test Specificity

Recognizes cyclin D1 in MCF-7 and A431 cells. Does not react with cyclins D2 and D3.

Content And Storage

2°C to 8°C

Isotype

IgG2a

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Description

  • Specifically detects Cyclin D1 Clone: DCS-6 in Human, Mouse, Rat samples, and it is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization, Immuno Blotting Cyclins are a family of proteins implicated in the induction and control of mitosis
  • They are characterized by their accumulation and dramatic destruction in a cell cycle dependent manner
  • Cyclins are necessary for cdc/cdk kinase activity and are one of the subunits of the active kinase, in association with cdc2 or one of the cdk family members
  • Several different major cyclin families have been identified to date
  • These include the A, B, D and E family of cyclins
  • The D family of cyclins has been associated with a wide variety of proliferative diseases but their biochemical role is still unknown
  • The D cyclins appear in early G1, before the B cyclins
  • The human cyclin D1 gene has been mapped to the 11q13 locus and has been shown to be the PRAD1 gene product
  • PRAD1 was originally identified as being a clonally rearranged and overexpressed gene linked to the bcl-1 locus in a subset of benign parathyroid tumors
  • Amplification of cyclin D1 genes has also been demonstrated in human esophageal cancer.

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Antigen:
Cyclin D1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization

Clone:
DCS-6

Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin.

Immunogen:
recombinant human cyclin D1

Regulatory Status:
RUO

Test Specificity:
Recognizes cyclin D1 in MCF-7 and A431 cells. Does not react with cyclins D2 and D3.

Content And Storage:
2°C to 8°C

Isotype:
IgG2a

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