ENM011B

IL-10 Monoclonal Antibody (12G8), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 ENM011B-Each-of-1 In Stock ₹ 44,533.98

ENM011B - Each of 1

₹ 44,533.98

In Stock

Quantity

1

Base Price: ₹ 44,533.98

GST (18%): ₹ 8,016.116

Total Price: ₹ 52,550.096

Antigen

IL-10

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 4% BSA and proprietary preservative

Gene Accession No.

P22301

Gene Symbols

IL10

Immunogen

Recombinant human IL-10 (COS cell-derived)

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA, Western Blot

Clone

12G8

Conjugate

Biotin

Gene

IL10

Gene Alias

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3586

Content And Storage

-20°C

Form

Liquid

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Description

  • M011B targets IL-10 in ELISA and Western blot applications and shows reactivity with human samples
  • The M011B immunogen is recombinant human IL-10 (COS cell-derived)
  • The original parent clone is 12G8 and has been subcloned as 2553.2.4
  • M011B detects IL-10 which has a predicted molecular weight of approximately 19 kDa
  • The M011B IL10 antibody (biotinylated conjugate of clone 12G8) has successfully been paired as the detection antibody in a sandwich ELISA with capture antibody M010 (clone 9D7)
  • Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection
  • Biotinylated antibody M011B (clone 12G8) and antibody M010 (clone 9D7) have successfully been used in combination with recombinant IL10 protein SIL10 in ELISA applications
  • This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice
  • The resulting ascites is collected from the mice and the antibody is purified
  • IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes
  • This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages
  • It also enhances B cell survival, proliferation, and antibody production
  • Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway
  • Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract
  • Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
  • Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Compare Similar Items

Show Difference

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Thermo Scientific

ENM011B

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Antigen:
IL-10

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 4% BSA and proprietary preservative

Gene Accession No.:
P22301

Gene Symbols:
IL10

Immunogen:
Recombinant human IL-10 (COS cell-derived)

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Western Blot

Clone:
12G8

Conjugate:
Biotin

Gene:
IL10

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3586

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

ENM121

--


Antigen:
IL-12/IL-23 p40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P29459, P29460, Q9NPF7

Gene Symbols:
IL12A, IL12B, Il23a

Immunogen:
COS cell-derived recombinant human IL-12, p40 subunit

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Inhibition Assays, Western Blot

Clone:
C8.6

Conjugate:
Unconjugated

Gene:
IL12A

Gene Alias:
CLMF; CLMF p35; CLMF p40; CLMF2; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12/IL 23p40; il 23; IL 23 p40; Il12; Il-12 p35; IL12 p40; IL23; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il12a; IL-12A; Il12b; IL-12B; IL12p35; IL-12p35; Il12p40; Il-12p40; il23; IL-23; IL23 p41; IL-23 subunit alpha; Il23a; IL-23A; IL-23-A; IL23P19; IL-23p19; IL35 subunit; ILN; IMD28; IMD29; Interleukin; Interleukin 12; interleukin 12 35 kDa subunit; interleukin 12 35kDa subunit; interleukin 12 40 kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 polypeptide 35; interleukin 12 subunit p40; interleukin 12, p35; interleukin 12, p40; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12b; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; Interleukin12; interleukin-12 alpha chain; interleukin-12 beta chain; interleukin-12 p40; interleukin-12 p40 subunit; interleukin-12 subunit alpha; Interleukin-12 subunit beta; interleukin-12 subunit p40; interleukin-23 p19 subunit; interleukin-23 p40 subunit; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; Ll12a; natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35; natural killer cell stimulatory factor, 40 kD subunit; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NK cell stimulatory factor chain 2; NKSF; NKSF1; NKSF2; p19; P35; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593, 51561

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

ENM121B

--


Antigen:
IL-12/IL-23 p40

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 4% BSA and proprietary preservative

Gene Accession No.:
P29459, P29460, Q9NPF7

Gene Symbols:
IL12A, IL12B, Il23a

Immunogen:
COS cell-derived recombinant human IL-12, p40 subunit

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Western Blot

Clone:
C8.6

Conjugate:
Biotin

Gene:
IL12B

Gene Alias:
CLMF; CLMF p35; CLMF p40; CLMF2; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12/IL 23p40; il 23; IL 23 p40; Il12; Il-12 p35; IL12 p40; IL23; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il12a; IL-12A; Il12b; IL-12B; IL12p35; IL-12p35; Il12p40; Il-12p40; il23; IL-23; IL23 p41; IL-23 subunit alpha; Il23a; IL-23A; IL-23-A; IL23P19; IL-23p19; IL35 subunit; ILN; IMD28; IMD29; Interleukin; Interleukin 12; interleukin 12 35 kDa subunit; interleukin 12 35kDa subunit; interleukin 12 40 kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 polypeptide 35; interleukin 12 subunit p40; interleukin 12, p35; interleukin 12, p40; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12b; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; Interleukin12; interleukin-12 alpha chain; interleukin-12 beta chain; interleukin-12 p40; interleukin-12 p40 subunit; interleukin-12 subunit alpha; Interleukin-12 subunit beta; interleukin-12 subunit p40; interleukin-23 p19 subunit; interleukin-23 p40 subunit; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; Ll12a; natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35; natural killer cell stimulatory factor, 40 kD subunit; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NK cell stimulatory factor chain 2; NKSF; NKSF1; NKSF2; p19; P35; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593, 51561

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

ENM122

--


Antigen:
IL-12

Classification:
Monoclonal

Concentration:
__

Formulation:
500μg Purified Antibody (1.06mg/ml) in PBS, with no preservative

Gene Accession No.:
P29459, P29460

Gene Symbols:
IL12A

Immunogen:
Recombinant human IL-12 (p70)

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
20C2

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
CLMF p35; IL-12 subunit p35; 20C2; IL-12, subunit p35; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12, p35; inter

Host Species:
Rat

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
3592, 3593

Content And Storage:
Store at -20°C

Form:
Purified