ENP420B

IL-1 beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 ENP420B-Each-of-1 In Stock ₹ 46,416.30

ENP420B - Each of 1

₹ 46,416.30

In Stock

Quantity

1

Base Price: ₹ 46,416.30

GST (18%): ₹ 8,354.934

Total Price: ₹ 54,771.234

Antigen

IL-1 beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL1B

Gene Alias

catabolin; cytokine; Hematopoietin 1 (H1); IFN beta inducing factor; il 1b; IL 1β; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; IL-1B; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1β; ILN; Interleukin; interleukin 1 beta; Interleukin 1 beta precursor; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; interleukin*1*beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1b; interleukin-1beta; interleukin-beta; LAF; lymphocyte proliferation-potentiating factor; Osteoclast activating factor (OAF); preinterleukin 1 beta; Pro interleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

16176, 3553

Content And Storage

-20°C

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Neutralization, Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P01584, P10749

Gene Symbols

IL1B

Immunogen

Recombinant human IL-1 beta

Quantity

1 mg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

ENMM425B

--

Img

Thermo Scientific

ENM420BB

--

Img

Thermo Scientific

ENPBOIL1BI

--

Img

Thermo Scientific

ENMM425BB

--

Img

Thermo Scientific

FEMA550586

--

Img

Thermo Scientific

ENP620

--

Img

Thermo Scientific

ENP420A

--

Img

Thermo Scientific

ENM421A

--

Description

  • P420B targets IL-1 beta in ELISA, IHC, Neu, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples
  • The P420B immunogen is recombinant human IL-1 beta
  • P420B detects IL-1 beta which has a predicted molecular weight of approximately 31 kDa
  • This product is a Low Endotoxin formulation
  • This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
  • Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells
  • IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol
  • Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals
  • Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta
  • IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 via an alternate and incompletely understood mechanism
  • Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions
  • IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha
  • IL-1 beta activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition
  • IL-1 beta play an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses to infection and injury
  • Elevated levels of IL-1 beta have been associated with many chronic inflammatory conditions IL-1 beta neutralizing antibodies potential therapeutic value.

Compare Similar Items

Show Difference

Img

Thermo Scientific

ENP420B

--


Antigen:
IL-1 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
catabolin; cytokine; Hematopoietin 1 (H1); IFN beta inducing factor; il 1b; IL 1β; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; IL-1B; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1β; ILN; Interleukin; interleukin 1 beta; Interleukin 1 beta precursor; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; interleukin*1*beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1b; interleukin-1beta; interleukin-beta; LAF; lymphocyte proliferation-potentiating factor; Osteoclast activating factor (OAF); preinterleukin 1 beta; Pro interleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16176, 3553

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Neutralization, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P01584, P10749

Gene Symbols:
IL1B

Immunogen:
Recombinant human IL-1 beta

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

ENP600

--


Antigen:
IL-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL2

Gene Alias:
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3558

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA

Concentration:
1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P60568

Gene Symbols:
IL2

Immunogen:
Recombinant human IL-2

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

ENP620

--


Antigen:
IL-6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il6

Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16193, 3569

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P05231, P08505

Gene Symbols:
Il6

Immunogen:
Recombinant human IL-6.

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

ENP802B

--


Antigen:
VEGF

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
VEGFA

Gene Alias:
angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7422

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 4% BSA and proprietary preservative

Gene Accession No.:
P15692

Gene Symbols:
VEGFA

Immunogen:
Human VEGF-A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG