FEMA549785

Phospho-FAK (Tyr397) Recombinant Rabbit Monoclonal Antibody (1B3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549785-Each-of-1 In Stock ₹ 35,764.08

FEMA549785 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Phospho-FAK (Tyr397)

Classification

Recombinant Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q05397

Gene Symbols

PTK2

Immunogen

A synthesized peptide derived from human Phospho-PTK2 (Y397)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

1B3

Conjugate

Unconjugated

Gene

PTK2

Gene Alias

CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5747

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
  • FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
  • FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
  • Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
  • Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
  • In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
  • In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
  • Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.

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Show Difference

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Thermo Scientific

FEMA549785

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Antigen:
Phospho-FAK (Tyr397)

Classification:
Recombinant Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q05397

Gene Symbols:
PTK2

Immunogen:
A synthesized peptide derived from human Phospho-PTK2 (Y397)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1B3

Conjugate:
Unconjugated

Gene:
PTK2

Gene Alias:
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5747

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549786

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Antigen:
MIP-3 beta

Classification:
Recombinant Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q99731

Gene Symbols:
Ccl19

Immunogen:
A synthesized peptide derived from human CCL19

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
3A12

Conjugate:
Unconjugated

Gene:
Ccl19

Gene Alias:
beta chemokine exodus-3, beta-chemokine exodus-3, CC chemokine ligand 19, C-C motif chemokine, C-C motif chemokine 19, C-C motif chemokine ligand 19, Ccl19, chemokine (C-C motif) ligand 19, chemokine CCL19, CK beta-11, CKb11, EBI1 ligand chemokine, EBI-1 ligand chemokine, EBI1-ligand chemokine, EBV-induced molecule 1 ligand chemokine, ELC, Epstein-Barr virus-induced molecule 1 ligand chemokine, exodus-3, macrophage inflammatory protein 3 beta, macrophage inflammatory protein 3-beta, MIP3B, MIP-3b, MIP-3-beta, M-MIP-3-beta, SCYA19, small inducible cytokine A19, small inducible cytokine subfamily A (Cys-Cys), member 19, small-inducible cytokine A19

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6363

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549787

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Antigen:
Cdc5L

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q99459

Gene Symbols:
CDC5L

Immunogen:
A synthesized peptide derived from human CDC5L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1E3

Conjugate:
Unconjugated

Gene:
CDC5L

Gene Alias:
1200002I02Rik, AA408004, CDC5, CDC5 cell division cycle 5-like, CDC5 cell division cycle 5-like (S. pombe), CDC5L, CDC5-LIKE, Cdc5-like protein, Cdc5-related protein, CEF1, cell division cycle 5 like, cell division cycle 5-like, cell division cycle 5-like (S. pombe), cell division cycle 5-like protein, cell division cycle 5-related protein, dJ319D22.1, dJ319D22.1 (CDC5-like protein), hCDC5, KIAA0432, Pcdc5rp, Pombe cdc5-related protein, Unknown (protein for MGC:128482), zgc:55853

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
988

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549790

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Antigen:
GluR2/GluR3

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P42262, P42263

Gene Symbols:
Gria2, Gria3

Immunogen:
A synthesized peptide derived from human GRIA2/GRIA3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Clone:
4C3

Conjugate:
Unconjugated

Gene:
Gria2

Gene Alias:
2900064I19Rik, AMPA selective glutamate receptor, AMPA-selective glutamate receptor 2, AMPA-selective glutamate receptor 3, dJ1171F9.1, GluA2, GluA3, GLUR2, GluR-2, GLUR3, GluR-3, Gluralpha3, GLURB, gluR-B, GLURC, GLUR-C, GluR-K2, GluR-K3, glutamate ionotropic receptor AMPA type subunit 2, glutamate ionotropic receptor AMPA type subunit 3, glutamate receptor, glutamate receptor 2, Glutamate receptor 3, glutamate receptor B, glutamate receptor B flip isoform, glutamate receptor C, glutamate receptor channel alpha3 subunit, glutamate receptor ionotropic, AMPA 2, Glutamate receptor ionotropic, AMPA 3, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3, glutamate receptor, ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 3, glutamate receptor, ionotropic, AMPA2 (alpha 2), glutamate receptor, ionotropic, AMPA3 (alpha 3), GPRC1C, GRIA2, GRIA3, GRM3, HBGR2, Kiaa4184, MGR3, MRX94

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2891, 2892

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG