FEMA549832
CXCR4 Recombinant Rabbit Monoclonal Antibody (2F10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549832-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549832 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
CXCR4
Classification
Recombinant Monoclonal
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P61073
Gene Symbols
Cxcr4
Immunogen
A synthesized peptide derived from human CXCR4
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry
Clone
2F10
Conjugate
Unconjugated
Gene
Cxcr4
Gene Alias
b2b220Clo, C Cmotif chemokine, C X C motif chemokine, CC motif chemokine, CCmotif chemokine, CD antigen CD184, CD184, CD184 antigen, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C) receptor 4, chemokine receptor, chemokine receptor (LCR1), chemokine receptor 4, chemokine receptor CXCR4, Cmkar4, CXC, CXC chemokine receptor, C-X-C chemokine receptor type 4, CXC motif chemokine, C-X-C motif chemokine receptor 4, CXCR4, CXC-R4, CXCR-4, D2S201E, FB22, Fusin, HM89, HSY3RR, HUMSTR, LAP3, LAP-3, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, leukocyte-expressed seven-transmembrane-domain, lipopolysaccharide-associated protein 3, LPS-associated protein 3, neuropeptide Y receptor Y3, neuropeptide Y3 receptor, NPY3R, NPYR, NPYRL, NPYY3R, PB-CKR, PBSF/SDF-1, pre-B-cell-derived chemokine receptor, SDF-1 receptor, Sdf1r, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor, WHIM, WHIMS
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7852
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells
- CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus
- In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells
- CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation
- CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels
- Also, CXCR4 is involved in hematopoiesis and in cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells
- In the CNS, CXCR4 could mediate hippocampal-neuron survival and is involved in cerebellar development
- CXCR4 binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes
- Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells
- The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.
Compare Similar Items
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Antigen: CXCR4
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P61073
Gene Symbols: Cxcr4
Immunogen: A synthesized peptide derived from human CXCR4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry
Clone: 2F10
Conjugate: Unconjugated
Gene: Cxcr4
Gene Alias: b2b220Clo, C Cmotif chemokine, C X C motif chemokine, CC motif chemokine, CCmotif chemokine, CD antigen CD184, CD184, CD184 antigen, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C) receptor 4, chemokine receptor, chemokine receptor (LCR1), chemokine receptor 4, chemokine receptor CXCR4, Cmkar4, CXC, CXC chemokine receptor, C-X-C chemokine receptor type 4, CXC motif chemokine, C-X-C motif chemokine receptor 4, CXCR4, CXC-R4, CXCR-4, D2S201E, FB22, Fusin, HM89, HSY3RR, HUMSTR, LAP3, LAP-3, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, leukocyte-expressed seven-transmembrane-domain, lipopolysaccharide-associated protein 3, LPS-associated protein 3, neuropeptide Y receptor Y3, neuropeptide Y3 receptor, NPY3R, NPYR, NPYRL, NPYY3R, PB-CKR, PBSF/SDF-1, pre-B-cell-derived chemokine receptor, SDF-1 receptor, Sdf1r, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor, WHIM, WHIMS
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7852
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
CXCR4
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P61073
Gene Symbols:
Cxcr4
Immunogen:
A synthesized peptide derived from human CXCR4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry
Clone:
2F10
Conjugate:
Unconjugated
Gene:
Cxcr4
Gene Alias:
b2b220Clo, C Cmotif chemokine, C X C motif chemokine, CC motif chemokine, CCmotif chemokine, CD antigen CD184, CD184, CD184 antigen, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C) receptor 4, chemokine receptor, chemokine receptor (LCR1), chemokine receptor 4, chemokine receptor CXCR4, Cmkar4, CXC, CXC chemokine receptor, C-X-C chemokine receptor type 4, CXC motif chemokine, C-X-C motif chemokine receptor 4, CXCR4, CXC-R4, CXCR-4, D2S201E, FB22, Fusin, HM89, HSY3RR, HUMSTR, LAP3, LAP-3, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, leukocyte-expressed seven-transmembrane-domain, lipopolysaccharide-associated protein 3, LPS-associated protein 3, neuropeptide Y receptor Y3, neuropeptide Y3 receptor, NPY3R, NPYR, NPYRL, NPYY3R, PB-CKR, PBSF/SDF-1, pre-B-cell-derived chemokine receptor, SDF-1 receptor, Sdf1r, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor, WHIM, WHIMS
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7852
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Myeloperoxidase
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P05164
Gene Symbols: MPO
Immunogen: A synthesized peptide derived from human Myeloperoxidase
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 2G11
Conjugate: Unconjugated
Gene: MPO
Gene Alias: 84 kDa myeloperoxidase, 89 kDa myeloperoxidase, mKIAA4033, MPO, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4353
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Myeloperoxidase
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P05164
Gene Symbols:
MPO
Immunogen:
A synthesized peptide derived from human Myeloperoxidase
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
2G11
Conjugate:
Unconjugated
Gene:
MPO
Gene Alias:
84 kDa myeloperoxidase, 89 kDa myeloperoxidase, mKIAA4033, MPO, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4353
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Neutrophil elastase
Classification: Recombinant Monoclonal
Concentration: 0.28 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P08246
Gene Symbols: ELANE
Immunogen: A synthesized peptide derived from human Neutrophil Elastase
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: 2H12
Conjugate: Unconjugated
Gene: ELANE
Gene Alias: bone marrow serine protease, ELA2, ELA2A, ELANE, Elastase, elastase 2, neutrophil, elastase, neutrophil expressed, Elastase2, elastase-2, F430011M15Rik, GE, granulocyte-derived elastase, HLE, HNE, Human leukocyte elastase, Leukocyte elastase, medullasin, NE, neutrophil elastase, PE-1, PMN elastase, PMN-E, polymorphonuclear elastase, SCN1, serine protease
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1991
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Neutrophil elastase
Classification:
Recombinant Monoclonal
Concentration:
0.28 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P08246
Gene Symbols:
ELANE
Immunogen:
A synthesized peptide derived from human Neutrophil Elastase
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
2H12
Conjugate:
Unconjugated
Gene:
ELANE
Gene Alias:
bone marrow serine protease, ELA2, ELA2A, ELANE, Elastase, elastase 2, neutrophil, elastase, neutrophil expressed, Elastase2, elastase-2, F430011M15Rik, GE, granulocyte-derived elastase, HLE, HNE, Human leukocyte elastase, Leukocyte elastase, medullasin, NE, neutrophil elastase, PE-1, PMN elastase, PMN-E, polymorphonuclear elastase, SCN1, serine protease
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1991
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Transthyretin
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P02766
Gene Symbols: TTR
Immunogen: A synthesized peptide derived from human Prealbumin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 3F6
Conjugate: Unconjugated
Gene: TTR
Gene Alias: AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7276
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Transthyretin
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P02766
Gene Symbols:
TTR
Immunogen:
A synthesized peptide derived from human Prealbumin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
3F6
Conjugate:
Unconjugated
Gene:
TTR
Gene Alias:
AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7276
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG