FEMA549884

Huntingtin Recombinant Rabbit Monoclonal Antibody (6F2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549884-Each-of-1 In Stock ₹ 35,764.08

FEMA549884 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Huntingtin

Classification

Recombinant Monoclonal

Concentration

0.63 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P42858

Gene Symbols

Htt

Immunogen

A synthesized peptide derived from human Huntingtin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

6F2

Conjugate

Unconjugated

Gene

Htt

Gene Alias

AI256365, C430023I11Rik, Hd, HD protein, HD protein homolog, Hdh, HTT, Huntingtin, huntingtin (Huntington disease), Huntingtin, myristoylated N-terminal fragment, Huntington disease gene homolog, huntington disease protein, huntington disease protein homolog, IT15, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3064

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Huntingtin is a disease gene linked to Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons
  • This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product
  • HD is a mid-life onset autosomal dominant neurodegenerative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years.The huntingtin locus is large, spanning 180 kb and consisting of 67 exons
  • The huntingtin gene is widely expressed and is required for normal development
  • It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues
  • The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed
  • The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein.

Compare Similar Items

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Thermo Scientific

FEMA549884

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Antigen:
Huntingtin

Classification:
Recombinant Monoclonal

Concentration:
0.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P42858

Gene Symbols:
Htt

Immunogen:
A synthesized peptide derived from human Huntingtin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
6F2

Conjugate:
Unconjugated

Gene:
Htt

Gene Alias:
AI256365, C430023I11Rik, Hd, HD protein, HD protein homolog, Hdh, HTT, Huntingtin, huntingtin (Huntington disease), Huntingtin, myristoylated N-terminal fragment, Huntington disease gene homolog, huntington disease protein, huntington disease protein homolog, IT15, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3064

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549885

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Antigen:
B-Raf

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P15056

Gene Symbols:
BRAF

Immunogen:
A synthesized peptide derived from human B Raf

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
6G3

Conjugate:
Unconjugated

Gene:
BRAF

Gene Alias:
94 kDa B-raf protein, 9930012E13Rik, AA120551, AA387315, AA473386, Braf, B-raf, B-raf protein, B-raf protein isoform 1, B-raf protein isoform 2, B-Raf proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-Raf proto-oncogene, serine/threonine kinase, Braf transforming gene, BRAF1, B-RAF1, Braf2, Braf-2, C230098H17, C87398, C-RMIL, D6Ertd631e, FLJ95109, MGC126806, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, proto-oncogene c-Rmil, RAFB1, RMIL, rmil serine/threonine-protein kinase, serine/threonine kinase, serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase Rmil, v-raf murine sarcoma viral oncogene homolog B, v-raf murine sarcoma viral oncogene homolog B1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
673

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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Antigen:
Cullin 3

Classification:
Recombinant Monoclonal

Concentration:
0.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q13618

Gene Symbols:
CUL3

Immunogen:
A synthesized peptide derived from human Cullin 3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
7B6

Conjugate:
Unconjugated

Gene:
CUL3

Gene Alias:
AI467304, AW146203, Cul3, CUL-3, cullin 3, cullin-3, KIAA0617, mKIAA0617, OTTHUMP00000203839, OTTHUMP00000203840, PHA2E

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8452

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549890

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Antigen:
IGFBP2

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P18065

Gene Symbols:
IGFBP2

Immunogen:
A synthesized peptide derived from human IGFBP2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
7G11

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832, BP2, BRL-BP, IBP2, IBP-2, IGF binding protein 2, IGF-binding protein 2, IGFBP, IGFBP2, IGFBP-2, IGF-BP53, ILGFBPA, Insulin like growth factor binding protein, insulin like growth factor binding protein 2, insulin-like growth factor binding protein 2, insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor-binding protein 2, mIGFBP-2, OTTHUMP00000207753

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3485

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG