FEMA549920

RIG-I Recombinant Rabbit Monoclonal Antibody (7F6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549920-Each-of-1 In Stock ₹ 35,764.08

FEMA549920 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

RIG-I

Classification

Recombinant Monoclonal

Concentration

3 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

A synthesized peptide derived from human DDX58

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

7F6

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

6430573D20Rik, C330021E21, Ddx58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, DEAD box protein 58, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, DEAD/H box polypeptide RIG-I, DEAD-box protein 58, DEXD/H-box helicase 58, probable ATP-dependent RNA helicase DDX58, Retinoic acid-inducible gene 1 protein, retinoic acid-inducible gene I protein, retinoic acid-inducible gene-I, RIG-1, RIGI, RIG-I, RIG-I-like receptor 1, RLR-1, RNA helicase RIG-I, SGMRT2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA549920

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Antigen:
RIG-I

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
A synthesized peptide derived from human DDX58

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
7F6

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
6430573D20Rik, C330021E21, Ddx58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, DEAD box protein 58, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, DEAD/H box polypeptide RIG-I, DEAD-box protein 58, DEXD/H-box helicase 58, probable ATP-dependent RNA helicase DDX58, Retinoic acid-inducible gene 1 protein, retinoic acid-inducible gene I protein, retinoic acid-inducible gene-I, RIG-1, RIGI, RIG-I, RIG-I-like receptor 1, RLR-1, RNA helicase RIG-I, SGMRT2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549922

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Antigen:
ILF3

Classification:
Recombinant Monoclonal

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q12906

Gene Symbols:
ILF3

Immunogen:
A synthesized peptide derived from human ILF3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
7H8

Conjugate:
Unconjugated

Gene:
ILF3

Gene Alias:
CBTF, Double-stranded RNA-binding protein 76, double-stranded RNA-binding protein, 76 kD, DRBF, DRBP76, dsRNA binding protein NFAR-2/MPP4, Ilf3, ilf3 protein, ilf3b, interleukin enhancer binding factor 3, interleukin enhancer binding factor 3, 90kD, interleukin enhancer binding factor 3, 90kDa, interleukin enhancer binding factor 3b, interleukin enhancer-binding factor 3, Interleukin enhancer-binding factor 3 homolog, M phase phosphoprotein 4, MBII-26, MMP4, M-phase phosphoprotein 4, MPHOSPH4, MPP4, NF110, NF110b, NF90, NF90a, NF90b, NFAR, NFAR-1, NFAR2, NF-AT-90, nuclear factor 90, nuclear factor associated with dsRNA, Nuclear factor of activated T-cells 90 kDa, nuclear factor of activated T-cells, 90 kD, TCP110, TCP80, Translational control protein 80, wu:fb37d07, wu:fb94b02, zgc:77030

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3609

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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Thermo Scientific

FEMA549923

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Antigen:
SMN1

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q16637

Gene Symbols:
SMN1

Immunogen:
A synthesized peptide derived from human SMN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
8B10

Conjugate:
Unconjugated

Gene:
SMN1

Gene Alias:
AI849087, BCD541, component of gems 1, Gemin1, Gemin-1, SMA, SMA@, SMA1, SMA2, SMA3, SMA4, Smn, SMN1, SMN2, SMNC, SMNT, survival motor neuron 1, survival motor neuron 1 protein, survival motor neuron protein, survival of motor neuron 1, telomeric, survival of motor neuron protein, T-BCD541, TDRD16A, tudor domain containing 16A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6606

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549924

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Antigen:
NONO

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q15233

Gene Symbols:
Nono

Immunogen:
A synthesized peptide derived from human NONO/p54nrb

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
8C11

Conjugate:
Unconjugated

Gene:
Nono

Gene Alias:
54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, AA407051, AV149256, DNA-binding p52/p100 complex, 52 kDa subunit, HGNC:7871, LOC100346936, MRXS34, NMT-1, NMT55, nonA, Nono, NonO protein, non-POU domain containing octamer binding, non-POU domain containing, octamer-binding, non-POU domain-containing octamer (ATGCAAAT) binding protein, non-POU domain-containing octamer-binding protein, non-POU-domain-containing, non-POU-domain-containing, octamer binding protein, non-POU-domain-containing, octamer-binding protein, NRB54, P54, p54(nrb), p54nrb, PPP1R114, protein phosphatase 1, regulatory subunit 114

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4841

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG