FEMA549976

ROR1 Recombinant Human Monoclonal Antibody (7H12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549976-Each-of-1 In Stock ₹ 35,764.08

FEMA549976 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

ROR1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

Q01973

Gene Symbols

ROR1

Immunogen

Recombinant Human ROR1 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Neutralization

Clone

7H12

Conjugate

Unconjugated

Gene

ROR1

Gene Alias

2810404D04Rik, dJ537F10.1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, MGC99659, mRor1, neurotrophic tyrosine kinase, receptor related 1, neurotrophic tyrosine kinase, receptor-related 1, Ntrkr1, receptor tyrosine kinase like orphan receptor 1, receptor tyrosine kinase-like orphan receptor 1, RGD1559469, ROR1, T-ROR1, tyrosine-protein kinase transmembrane receptor ROR1

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4919

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG1

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Description

  • Description Receptor-tyrosine-kinase-like orphan receptor 1 (ROR1) is a tumor-associated, surface protein predominantly expressed during embryogenesis, where it is involved in organ morphogenesis, nervous system development, and neural progenitor cell maintenance and survival
  • Virtually absent from normal pediatric and adult tissues, with the exception of low-level expression in a subset of immature b cell precursors known as hematogones and adipocytes, ROR1 is notably overexpressed, and considered a survival factor, in a number of B lymphoid and epithelial malignancies: including chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), acute lymphoblastic leukemia (ALL), marginal zone lymphoma, lung adenocarcinoma
  • First identified during PCR-based cloning of a human neuroblastoma cell line in search of tyrosine kinases similar to tropomyosin-receptor-kinase (Trk) neurotropic receptors, ROR1, along with the related receptor tyrosine kinase (RTK) ROR2, was catalogued as an &quoteorphan&quote receptor due to the fact its related ligand remained elusive
  • Wnt-5a has since been suggested as a candidate ligand for ROR1, and ROR1 has been implicated to function as a pseudokinase, promoting proliferation and resistance to apoptosis in cancer cells through interaction with Wnt-5a, and TCL1-co-activation of AKT
  • ROR1 is expressed as a glycoprotein containing extracellular immunoglobulin (Ig)-like, Frizzled, and Kringle domains, as well as an intracellular region containing a tyrosine kinase domain.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA549976

--


Antigen:
ROR1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q01973

Gene Symbols:
ROR1

Immunogen:
Recombinant Human ROR1 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Neutralization

Clone:
7H12

Conjugate:
Unconjugated

Gene:
ROR1

Gene Alias:
2810404D04Rik, dJ537F10.1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, MGC99659, mRor1, neurotrophic tyrosine kinase, receptor related 1, neurotrophic tyrosine kinase, receptor-related 1, Ntrkr1, receptor tyrosine kinase like orphan receptor 1, receptor tyrosine kinase-like orphan receptor 1, RGD1559469, ROR1, T-ROR1, tyrosine-protein kinase transmembrane receptor ROR1

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4919

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

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FEMA549977

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Antigen:
C5AR1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
P21730

Gene Symbols:
C5AR1

Immunogen:
Recombinant Human C5AR1 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
3A7

Conjugate:
Unconjugated

Gene:
C5AR1

Gene Alias:
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
728

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

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FEMA549979

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Antigen:
CD74

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
P04233

Gene Symbols:
CD74

Immunogen:
Recombinant Human CD74 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
6B4

Conjugate:
Unconjugated

Gene:
CD74

Gene Alias:
CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 molecule, Cd74 molecule, major histocompatibility complex, class II invariant chain, class II-associated invariant chain peptide, CLIP, DHLAG, dinucleotide microsatellite, gamma chain of class II antigens, H-2 class II histocompatibility antigen gamma chain, histocompatibility: class II antigens, gamma chain of, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, invariant polypeptide of major histocompatibility complex, class II antigen-associated, INVG34, MHC class II-associated invariant chain, MHC HLA-DR gamma chain, p33

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
972

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

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FEMA549980

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Antigen:
CXCR4

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
P61073

Gene Symbols:
Cxcr4

Immunogen:
Recombinant Human CXCR4 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
2D4

Conjugate:
Unconjugated

Gene:
Cxcr4

Gene Alias:
b2b220Clo, C Cmotif chemokine, C X C motif chemokine, CC motif chemokine, CCmotif chemokine, CD antigen CD184, CD184, CD184 antigen, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C) receptor 4, chemokine receptor, chemokine receptor (LCR1), chemokine receptor 4, chemokine receptor CXCR4, Cmkar4, CXC, CXC chemokine receptor, C-X-C chemokine receptor type 4, CXC motif chemokine, C-X-C motif chemokine receptor 4, CXCR4, CXC-R4, CXCR-4, D2S201E, FB22, Fusin, HM89, HSY3RR, HUMSTR, LAP3, LAP-3, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, leukocyte-expressed seven-transmembrane-domain, lipopolysaccharide-associated protein 3, LPS-associated protein 3, neuropeptide Y receptor Y3, neuropeptide Y3 receptor, NPY3R, NPYR, NPYRL, NPYY3R, PB-CKR, PBSF/SDF-1, pre-B-cell-derived chemokine receptor, SDF-1 receptor, Sdf1r, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor, WHIM, WHIMS

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7852

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG4