FEMA549986

MST2 Recombinant Rabbit Monoclonal Antibody (3C3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549986-Each-of-1 In Stock ₹ 35,764.08

FEMA549986 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

MST2

Classification

Recombinant Monoclonal

Concentration

0.4 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q13188

Gene Symbols

STK3

Immunogen

A synthesized peptide derived from human STK3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

3C3

Conjugate

Unconjugated

Gene

STK3

Gene Alias

0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6788

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • STK3 (MST2) is a STE kinase family member that acts upstream of the MAP kinase signaling pathways, and is known to be activated by the proapoptotic stimuli staurosporine and FAS ligand
  • STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
  • It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
  • STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA549986

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Antigen:
MST2

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q13188

Gene Symbols:
STK3

Immunogen:
A synthesized peptide derived from human STK3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
3C3

Conjugate:
Unconjugated

Gene:
STK3

Gene Alias:
0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6788

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549988

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Antigen:
14-3-3 beta

Classification:
Recombinant Monoclonal

Concentration:
0.11 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P31946, P35213, Q9CQV8

Gene Symbols:
YWHAB

Immunogen:
A synthesized peptide derived from human YWHAB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
6F6

Conjugate:
Unconjugated

Gene:
YWHAB

Gene Alias:
1300003C17Rik, 14-3-3 alpha, 14-3-3 protein beta, 14-3-3 protein beta/alpha, 14-3-3 protein beta/alpha, N-terminally processed, 14-3-3 protein beta-subtype, 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide, brain protein 14-3-3, beta isoform, epididymis secretory protein Li 1, GW128, HEL-S-1, HS1, hypothetical protein GW128, KCIP 1, KCIP1, KCIP-1, Prepronerve growth factor RNH-1, protein 1054, Protein kinase C inhibitor protein 1, protein kinase C inhibitor protein-1, QccE-16215, RP1-148E22.1, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide, tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, unnamed protein product, YWHAA, Ywhab

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54401, 56011, 7529

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549989

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Antigen:
HSP90 beta

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P08238

Gene Symbols:
Hsp90ab1

Immunogen:
A synthesized peptide derived from human HSP90AB1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7G7

Conjugate:
Unconjugated

Gene:
Hsp90ab1

Gene Alias:
90kDa, 90-kDa heat shock protein beta, AL022974, C81438, D6S182, heat shock 84 kDa, heat shock 90 kDa protein, heat shock 90kD protein 1, beta, heat shock 90kDa protein 1, beta, heat shock cognate protein HSP 90-beta, Heat shock protein, heat shock protein 1, beta, heat shock protein 90 alpha (cytosolic), class B member 1, heat shock protein 90 alpha family class B member 1, heat shock protein 90 beta, heat shock protein 90 kDa, heat shock protein 90 kDa alpha class B member 1, heat shock protein 90kDa alpha (cytosolic), class B member 1, heat shock protein 90kDa alpha family class B member 1, Heat shock protein HSP 90-beta, heat shock protein, 84 kDa 1, HSP, HSP 84, HSP 90, Hsp84, Hsp84-1, Hsp90, hsp90 beta, HSP90AB1, HSP90B, HSP90-beta, HSPC2, HSPCB, retinal degeneration slow protein, RP1-302G2.1, TSTA, Tumor-specific transplantation 84 kDa antigen, Unknown (protein for IMAGE:7943063)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3326

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549991

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Antigen:
LMO2

Classification:
Recombinant Monoclonal

Concentration:
0.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P25791

Gene Symbols:
Lmo2

Immunogen:
A synthesized peptide derived from human LMO2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
9H9

Conjugate:
Unconjugated

Gene:
Lmo2

Gene Alias:
cysteine-rich protein TTG-2, LIM domain only 2, LIM domain only 2 (rhombotin-like 1), LIM domain only protein 2, LIM domain only-2, LIM only 2, LMO2, LMO-2, LMO2 protein, Rbtn2, Rbtn-2, RBTNL1, RHOM2, Rhom-2, rhombotin 2, rhombotin-2, rhombotin-like 1, si:dkey-10o6.5, T-cell translocation gene 2, T-cell translocation protein 2, TTG2, wu:fc83a08, zgc:111930, zlmo2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4005

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG