FEMA550002

STAT4 Recombinant Rabbit Monoclonal Antibody (26G2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550002-Each-of-1 In Stock ₹ 35,764.08

FEMA550002 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

STAT4

Classification

Recombinant Monoclonal

Concentration

1.05 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q14765

Gene Symbols

STAT4

Immunogen

A synthesized peptide derived from human STAT4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

26G2

Conjugate

Unconjugated

Gene

STAT4

Gene Alias

CIS4, HSPC060, OTTHUMP00000163553, Signal transducer and activator of transcription 4, SLEB11, SOCS4, SOCS6, SSI4, STAI4, STAT, Stat4, STATI4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6775

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Related Products

Img

Thermo Scientific

FEMA550001

--

Img

Thermo Scientific

FEMA549897

--

Img

Thermo Scientific

FEMA549887

--

Img

Thermo Scientific

FEMA550028

--

Img

Thermo Scientific

FEMA550062

--

Img

Thermo Scientific

FEMA549800

--

Img

Thermo Scientific

FEMA549951

--

Img

Thermo Scientific

FEMA550016

--

Description

  • STAT4 was originally identified using degenerate primers complementary to sequences encoding conserved regions of other STAT proteins
  • The STAT4 protein is most similar to STAT1 (52%) and STAT3 (47%)
  • Functionally, STAT4 is similar to other STAT family members in that it can be tyrosine phosphorylated by Jak1 or Jak2
  • STAT4 forms homodimers and heterodimers with related STAT family members
  • Tyrosine phosphorylated STAT4 can bind the IFN-gamma activated site (GAS)
  • Serine phosphorylation of STAT is also required for maximal transcriptional activity
  • STAT4 expression is restricted to the thymus, spleen and testis
  • Until recently the cytokine(s) responsible for activation of STAT4 had not been identified
  • STAT4 is now known to be activated by the cytokine interleukin 12 (IL-12)
  • IL-12 is required for the T-cell independent induction of IFN-gamma which is a key step in the initial suppression of bacterial and parasitic infections
  • In addition, IL-12 is required for the development of a Th1 response which is necessary for effective host defense against intracellular pathogens
  • STAT4-deficient mice display impaired IL-12 development of Th1 cells and enhanced development of Th2 cells
  • A recent study in mouse has shown that in response to viral infection IFN-a/b activation of STAT4 is required for IFN-g production.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550002

--


Antigen:
STAT4

Classification:
Recombinant Monoclonal

Concentration:
1.05 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q14765

Gene Symbols:
STAT4

Immunogen:
A synthesized peptide derived from human STAT4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
26G2

Conjugate:
Unconjugated

Gene:
STAT4

Gene Alias:
CIS4, HSPC060, OTTHUMP00000163553, Signal transducer and activator of transcription 4, SLEB11, SOCS4, SOCS6, SSI4, STAI4, STAT, Stat4, STATI4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6775

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550004

--


Antigen:
USP14

Classification:
Recombinant Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P54578

Gene Symbols:
Usp14

Immunogen:
A synthesized peptide derived from human USP14

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
28C4

Conjugate:
Unconjugated

Gene:
Usp14

Gene Alias:
2610005K12Rik, 2610037B11Rik, ataxia, AW107924, ax, C78769, deubiquitinating enzyme 14, dUB-type TGT for deubiquitinating enzyme, nmf375, TGT, tRNA-guanine transglycosylase, 60-kD subunit, ubiquitin carboxyl-terminal hydrolase 14, ubiquitin specific peptidase 14, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase), ubiquitin specific protease 14, ubiquitin specific protease 14 (tRNA-guanine transglycosylase), ubiquitin thioesterase 14, ubiquitin thiolesterase 14, ubiquitin-specific processing protease 14, ubiquitin-specific-processing protease 14, Usp14, wu:fk63d09, zgc:55949

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9097

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550005

--


Antigen:
PSME1

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q06323

Gene Symbols:
PSME1

Immunogen:
A synthesized peptide derived from human PSME1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
29D5

Conjugate:
Unconjugated

Gene:
PSME1

Gene Alias:
11S regulator complex subunit alpha, 29-kD MCP activator subunit, activator of multicatalytic protease subunit 1, AW413925, epididymis secretory sperm binding protein Li 129m, HEL-S-129m, I79_008549, IFI5111, IGUP I-5111, interferon gamma up-regulated I-5111 protein, interferon-gamma IEF SSP 5111, interferon-gamma-inducible protein 5111, MGC8628, OTTHUMP00000164702, PA28 alpha subunit, PA28a, PA28alpha, protease (prosome, macropain) 28 subunit, alpha, proteasome (prosome, macropain) 28 subunit, alpha, proteasome (prosome, macropain) activator subunit 1, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), proteasome activator 28 subunit alpha, Proteasome activator complex subunit 1, proteasome activator subunit 1, Psme1, REGalpha, REG-alpha

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5720

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550006

--


Antigen:
RPS19

Classification:
Recombinant Monoclonal

Concentration:
1.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P39019

Gene Symbols:
RPS19

Immunogen:
A synthesized peptide derived from human RPS19

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
7E6

Conjugate:
Unconjugated

Gene:
RPS19

Gene Alias:
40S ribosomal protein S19, DBA, DBA1, Dsk3, HGNC:10402, ribosomal protein S19, Rps19, S19, Small ribosomal subunit protein eS19

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6223

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG