FEMA550091

IL-17A Recombinant Human Monoclonal Antibody (11C11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550091-Each-of-1 In Stock ₹ 35,764.08

FEMA550091 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

IL-17A

Classification

Recombinant Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

Q16552

Gene Symbols

IL17A

Immunogen

Recombinant Human IL17A protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Neutralization

Clone

11C11

Conjugate

Unconjugated

Gene

IL17A

Gene Alias

Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3605

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG4

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Description

  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550091

--


Antigen:
IL-17A

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Immunogen:
Recombinant Human IL17A protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
11C11

Conjugate:
Unconjugated

Gene:
IL17A

Gene Alias:
Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG4

Img

Thermo Scientific

FEMA550092

--


Antigen:
VSIG4

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q9Y279

Gene Symbols:
VSIG4

Immunogen:
Recombinant Human VSIG4 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
12D12

Conjugate:
Unconjugated

Gene:
VSIG4

Gene Alias:
A530061A11, BC025105, complement receptor of the immunoglobulin superfamily, CRIg, Ig superfamily protein, MGC137243 protein, protein Z39Ig, UNQ317/PRO362, V-set and immunoglobulin domain containing 4, V-set and immunoglobulin domain-containing protein 4, VSIG4, Z39IG

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11326

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

Img

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FEMA550093

--


Antigen:
SLC39A6

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q13433

Gene Symbols:
SLC39A6

Immunogen:
Recombinant Human SLC39A6 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
13F1

Conjugate:
Unconjugated

Gene:
SLC39A6

Gene Alias:
EMBL:AAH97493.1}, endoplasmic reticulum membrane protein, endoplasmic reticulum membrane-linked protein, Ermelin, Estrogen-regulated protein LIV-1, LIV1, LIV-1, LIV-1 protein, estrogen regulated, SLC39A6, slc39a6 {ECO:0000312, solute carrier family 39 (metal ion transporter), member 6, solute carrier family 39 (zinc transporter), member 6, solute carrier family 39 member 6, Zinc transporter ZIP6, Zip6, ZIP-6, zrt- and Irt-like protein 6

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25800

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

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Thermo Scientific

FEMA550095

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Antigen:
CDH17

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q12864

Gene Symbols:
Cdh17

Immunogen:
Recombinant Human CDH17 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Neutralization

Clone:
10B3

Conjugate:
Unconjugated

Gene:
Cdh17

Gene Alias:
BILL-cadherin, Cadherin, cadherin 17, cadherin 17, LI cadherin (liver-intestine), cadherin-16, cadherin-17, CDH16, CDH17, FLJ26931, HPT1, HPT-1, HPT-1 cadherin, HPT-1/LI, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1, intestinal peptide-associated transporter HPT-1, LI cadherin, LI-cadherin, Liver-intestine cadherin, MGC138218, MGC142024, P130

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1015

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1