FEMA550168

HSD3B1 Recombinant Rabbit Monoclonal Antibody (10G2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550168-Each-of-1 In Stock ₹ 35,764.08

FEMA550168 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

HSD3B1

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P14060

Gene Symbols

HSD3B1

Immunogen

A synthesized peptide derived from Human HSD3B1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

10G2

Conjugate

Unconjugated

Gene

HSD3B1

Gene Alias

3 beta-hydroxysteroid dehydrogenase 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3BETAHSD; 3-beta-HSD; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; 3BH; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase; HGNC:5217; HSD3B; Hsd3b1; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; hydroxysteroid dehydrogenase-1, delta<5>-3-beta; I; Progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; Trophoblast antigen FDO161G; unnamed protein product

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3283

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Related Products

Img

Thermo Scientific

FEMA549952

--

Img

Thermo Scientific

FEMA550054

--

Img

Thermo Scientific

FEMA551257

--

Img

Thermo Scientific

FEMA551284

--

Img

Thermo Scientific

FEMA544585

--

Img

Thermo Scientific

FEMA550068

--

Img

Thermo Scientific

FEMA549829

--

Img

Thermo Scientific

FEMA549834

--

Description

  • Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
  • Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
  • The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
  • Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
  • Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
  • The remnant protein is processed by another protease, gamma-secretase
  • Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
  • Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
  • The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
  • Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
  • Alzheimer's disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
  • Beta amyloid deposits are also detected in Lewy body dementia, Down's syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550168

--


Antigen:
HSD3B1

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P14060

Gene Symbols:
HSD3B1

Immunogen:
A synthesized peptide derived from Human HSD3B1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
10G2

Conjugate:
Unconjugated

Gene:
HSD3B1

Gene Alias:
3 beta-hydroxysteroid dehydrogenase 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3BETAHSD; 3-beta-HSD; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; 3BH; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase; HGNC:5217; HSD3B; Hsd3b1; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; hydroxysteroid dehydrogenase-1, delta<5>-3-beta; I; Progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; Trophoblast antigen FDO161G; unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3283

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550169

--


Antigen:
PKN2

Classification:
Recombinant Monoclonal

Concentration:
2.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q16513

Gene Symbols:
PKN2

Immunogen:
A synthesized peptide derived from Human PKN2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
11H3

Conjugate:
Unconjugated

Gene:
PKN2

Gene Alias:
6030436C20Rik, AI507382, cardiolipin-activated protein kinase Pak2, p140 kinase, PAK2, Pak-2, PKN gamma, PKN2, PRK2, PRKCL2, PRO2042, protease-activated kinase 2, protein kinase C-like 2, protein kinase N2, protein-kinase C-related kinase 2, RP5-905H16.1, serine/threonine kinase 7, serine/threonine-protein kinase N2, serine/threonine-protein kinase N2, serine/threonine-protein kinase N2-like, si:ch211-83f14.1, Stk7, wu:fa97c07

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5586

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550170

--


Antigen:
LEF1

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q9UJU2

Gene Symbols:
LEF1

Immunogen:
A synthesized peptide derived from Human LEF1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
13B7

Conjugate:
Unconjugated

Gene:
LEF1

Gene Alias:
3000002B05, AI451430, DKFZp586H0919, FLJ46390, HGNC:6551, HMG Binding Domain, LEF1, Lef-1, lymphoid enhancer binding factor 1, lymphoid enhancer binding factor 1 short isoform, lymphoid enhancer-binding factor 1, OTTHUMP00000219736, OTTHUMP00000219737, T cell-specific transcription factor 1-alpha, TCF10, TCF1ALPHA, TCF1-alpha, TCF7L3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51176

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550171

--


Antigen:
Uteroglobin

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P11684

Gene Symbols:
SCGB1A1

Immunogen:
A synthesized peptide derived from Human SCGB1A1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
21B2

Conjugate:
Unconjugated

Gene:
SCGB1A1

Gene Alias:
Blastokinin, CC10, CC16, CCPBP, CCSP, Clara cell 17 kDa protein, clara cell phospholipid-binding protein, clara cell secretory protein, clara cells 10 kDa secretory protein, PCBB, PCB-binding protein, PCB-BP, SCGB1A1, Secretoglobin family 1A member 1, secretoglobin, family 1A, member 1 (uteroglobin), UG, Ugb, UP1, UP-1, Urinary protein 1, urine protein 1, uteroglobin, Uteroglobin (Clara cell secretory protein), Utg

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7356

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG