FEMA550178

Nanog Recombinant Rabbit Monoclonal Antibody (2G6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550178-Each-of-1 In Stock ₹ 35,764.08

FEMA550178 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Nanog

Classification

Recombinant Monoclonal

Concentration

0.4 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q9H9S0

Gene Symbols

NANOG

Immunogen

A synthesized peptide derived from Human NANOG

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry

Clone

2G6

Conjugate

Unconjugated

Gene

NANOG

Gene Alias

2410002E02Rik, early embryo specific expression NK family, early embryo specific expression NK-type homeobox protein, Ecat4, ENK, ES cell-associated protein 4, FLJ12581, HGNC:20857, hNanog, Homeobox protein NANOG, homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48, Nanog, Nanog homeobox

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79923

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
  • NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
  • Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
  • Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
  • Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
  • Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
  • Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
  • The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
  • Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
  • Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
  • When overexpressed, NANOG promotes cells to enter into S phase and proliferation
  • Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550178

--


Antigen:
Nanog

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q9H9S0

Gene Symbols:
NANOG

Immunogen:
A synthesized peptide derived from Human NANOG

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
2G6

Conjugate:
Unconjugated

Gene:
NANOG

Gene Alias:
2410002E02Rik, early embryo specific expression NK family, early embryo specific expression NK-type homeobox protein, Ecat4, ENK, ES cell-associated protein 4, FLJ12581, HGNC:20857, hNanog, Homeobox protein NANOG, homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48, Nanog, Nanog homeobox

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79923

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550180

--


Antigen:
WNK1

Classification:
Recombinant Monoclonal

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q9H4A3

Gene Symbols:
WNK1

Immunogen:
A synthesized peptide derived from Human WNK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
26G7

Conjugate:
Unconjugated

Gene:
WNK1

Gene Alias:
6430573H23Rik, EG406236, Erythrocyte 65 kDa protein, HSAN2, HSN2, hWNK1, KDP, KIAA0344, Kinase deficient protein, MGC163339, MGC163341, mKIAA0344, p65, PPP1R167, Prkwnk1, prostate-derived sterile 20-like kinase, protein kinase lysine-deficient 1, Protein kinase with no lysine 1, protein phosphatase 1, regulatory subunit 167, PSK, Serine/threonine-protein kinase WNK1, serine/threonine-protein kinase WNK1 1, serine/threonine-protein kinase WNK1 2, With no K, WNK lysine deficient protein kinase 1, WNK lysine deficient protein kinase 1 isoform, WNK1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
65125

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550182

--


Antigen:
PITX3

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O75364

Gene Symbols:
PITX3

Immunogen:
A synthesized peptide derived from Human PITX3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry

Clone:
28A9

Conjugate:
Unconjugated

Gene:
PITX3

Gene Alias:
ak, aphakia, ASMD, ASOD, CTPP4, CTRCT11, Homeobox protein PITX3, homeobox protein PTX3, MGC12766, paired like homeodomain 3, paired-like homeodomain 3, paired-like homeodomain transcription factor 3, Pituitary homeobox 3, Pituitary homeobox 3 (Homeobox protein PITX3), PITX3, Ptx3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5309

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550183

--


Antigen:
FDPS

Classification:
Recombinant Monoclonal

Concentration:
0.6 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P14324

Gene Symbols:
FDPS

Immunogen:
A synthesized peptide derived from Human FDPS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
12H4

Conjugate:
Unconjugated

Gene:
FDPS

Gene Alias:
(2E,6E)-farnesyl diphosphate synthase, 6030492I17Rik, Ac2-125, AI256750, cholesterol-regulated 39 kDa protein, CR 39, dimethylallyltranstransferase, Farnesyl diphosphate synthase, farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase), farnesyl diphosphate synthetase, farnesyl pyrophosphate synthase, farnesyl pyrophosphate synthetase, farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase, Fdps, Fdpsl1, FPP synthase, FPP synthetase, FPPS, FPS, geranyltranstransferase, KIAA1293, mKIAA1293, POROK9, testis-specific farnesyl pyrophosphate synthetase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2224

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG