FEMA550289

SMURF1 Monoclonal Antibody (1A9H4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550289-Each-of-1 In Stock ₹ 35,764.08

FEMA550289 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

SMURF1

Classification

Monoclonal

Concentration

0.95 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide, pH 7.3

Gene Accession No.

Q9HCE7

Gene Symbols

Smurf1

Immunogen

Recombinant Human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

1A9H4

Conjugate

Unconjugated

Gene

Smurf1

Gene Alias

4930431E10Rik, E3 ubiquitin ligase SMURF1, E3 ubiquitin ligase SMURF2, E3 ubiquitin-protein ligase SMURF1, E3 ubiquitin-protein ligase SMURF2, HECT-type E3 ubiquitin transferase SMURF1, HECT-type E3 ubiquitin transferase SMURF2, hSMURF1, hSMURF2, KIAA1625, mKIAA1625, RGD1309707, SMAD specific E3 ubiquitin protein ligase 1, SMAD specific E3 ubiquitin protein ligase 2, Smad ubiquitination regulatory factor 1, SMAD ubiquitination regulatory factor 2, Smad-specific E3 ubiquitin ligase 1, SMAD-specific E3 ubiquitin-protein ligase 1, SMAD-specific E3 ubiquitin-protein ligase 2, SMURF1, SMURF2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

57154

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG2a

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Description

  • Members of the transforming growth factor-beta (TGFB) family signal through type I and type II serine/threonine-kinase receptors, which in turn activate the SMAD signaling pathway
  • Bone morphogenetic protein (BMP) receptors target SMAD1, SMAD5, and SMAD8, whereas receptors for activin and TGFB (e
  • g., ACVR1 and TGFBR1, respectively) target SMAD2 and SMAD3
  • Phosphorylation of these receptor-regulated SMADs induces their association with the common-partner SMAD, SMAD4
  • Smurf1, a HECT domain E3 ubiquitin ligase, regulates cell polarity and protrusive activity and is required to maintain the transformed morphology and motility of a tumor cell
  • Atypical protein kinase C-zeta (PKC2), an effector of the Cdc42/Rac1-PAR6 polarity complex, recruits Smurf1 to cellular protrusions, where it controlled the local level of RhoA
  • Smurf1 thus links the polarity complex to degradation of RhoA in lamellipodia and filopodia to prevent RhoA signaling during dynamic membrane movements.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550289

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Antigen:
SMURF1

Classification:
Monoclonal

Concentration:
0.95 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide, pH 7.3

Gene Accession No.:
Q9HCE7

Gene Symbols:
Smurf1

Immunogen:
Recombinant Human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1A9H4

Conjugate:
Unconjugated

Gene:
Smurf1

Gene Alias:
4930431E10Rik, E3 ubiquitin ligase SMURF1, E3 ubiquitin ligase SMURF2, E3 ubiquitin-protein ligase SMURF1, E3 ubiquitin-protein ligase SMURF2, HECT-type E3 ubiquitin transferase SMURF1, HECT-type E3 ubiquitin transferase SMURF2, hSMURF1, hSMURF2, KIAA1625, mKIAA1625, RGD1309707, SMAD specific E3 ubiquitin protein ligase 1, SMAD specific E3 ubiquitin protein ligase 2, Smad ubiquitination regulatory factor 1, SMAD ubiquitination regulatory factor 2, Smad-specific E3 ubiquitin ligase 1, SMAD-specific E3 ubiquitin-protein ligase 1, SMAD-specific E3 ubiquitin-protein ligase 2, SMURF1, SMURF2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57154

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG2a

Img

Thermo Scientific

FEMA550290

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Antigen:
PRDX3

Classification:
Monoclonal

Concentration:
1.258 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide, pH 7.3

Gene Accession No.:
P30048

Gene Symbols:
PRDX3

Immunogen:
Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein (63-256AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
12A10C12

Conjugate:
Unconjugated

Gene:
PRDX3

Gene Alias:
antioxidant protein, antioxidant protein 1, anti-oxidant protein 1, Aop1, AOP-1, AW822249, D0Tohi1, Ef2l, HBC189, Mer5, mitochondrial thioredoxin dependent peroxide reductase, mitochondrial Trx dependent peroxide reductase, perioredoxin-3, peroxiredoxin 3, peroxiredoxin III, Peroxiredoxin-3, Prdx3, PRO1748, Protein MER5, Protein MER5 homolog, Prx, Prx 3, PRx III, Prx3, PRX-3, Prx-III, SP22, SP-22, TDXM, thioredoxin-dependent peroxide reductase, mitochondrial

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10935

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG2b

Img

Thermo Scientific

FEMA550291

--


Antigen:
PRDX3

Classification:
Monoclonal

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide, pH 7.3

Gene Accession No.:
P30048

Gene Symbols:
PRDX3

Immunogen:
Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein (63-256AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
6E6E12

Conjugate:
Unconjugated

Gene:
PRDX3

Gene Alias:
antioxidant protein, antioxidant protein 1, anti-oxidant protein 1, Aop1, AOP-1, AW822249, D0Tohi1, Ef2l, HBC189, Mer5, mitochondrial thioredoxin dependent peroxide reductase, mitochondrial Trx dependent peroxide reductase, perioredoxin-3, peroxiredoxin 3, peroxiredoxin III, Peroxiredoxin-3, Prdx3, PRO1748, Protein MER5, Protein MER5 homolog, Prx, Prx 3, PRx III, Prx3, PRX-3, Prx-III, SP22, SP-22, TDXM, thioredoxin-dependent peroxide reductase, mitochondrial

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10935

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

Img

Thermo Scientific

FEMA550294

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Antigen:
Claudin 18

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P56856

Gene Symbols:
Cldn18

Immunogen:
Synthesized peptide derived from human Claudin 18

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
2F8

Conjugate:
Unconjugated

Gene:
Cldn18

Gene Alias:
claudin 18, claudin 18-like, claudin-18, CLDN18, SFTA5, SFTPJ, surfactant associated 5, surfactant associated protein J, surfactant, pulmonary associated protein J, UNQ778/PRO1572

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51208

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1 λ