FEMA550456

RIP1 Recombinant Rabbit Monoclonal Antibody (HL2250), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550456-Each-of-1 In Stock ₹ 39,785.40

FEMA550456 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

RIP1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q13546

Gene Symbols

RIPK1

Immunogen

Recombinant fragment of human RIP.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

HL2250

Conjugate

Unconjugated

Gene

RIPK1

Gene Alias

cell death protein RIP, D330015H01Rik, FLJ39204, OTTHUMP00000015955, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting serine/threonine kinase 1, receptor-interacting protein 1, receptor-interacting protein kinase 1, receptor-interacting serine/threonine-protein kinase 1, Rinp, RIP, RIP1, RIP-1, RIP1 (CT), RIPK1, serine/threonine-protein kinase RIP

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

8737

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
  • Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
  • Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
  • Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
  • Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
  • Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
  • RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550456

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Antigen:
RIP1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q13546

Gene Symbols:
RIPK1

Immunogen:
Recombinant fragment of human RIP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2250

Conjugate:
Unconjugated

Gene:
RIPK1

Gene Alias:
cell death protein RIP, D330015H01Rik, FLJ39204, OTTHUMP00000015955, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting serine/threonine kinase 1, receptor-interacting protein 1, receptor-interacting protein kinase 1, receptor-interacting serine/threonine-protein kinase 1, Rinp, RIP, RIP1, RIP-1, RIP1 (CT), RIPK1, serine/threonine-protein kinase RIP

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8737

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550457

--


Antigen:
SDHB

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P21912, P21913, Q9CQA3

Gene Symbols:
Sdhb

Immunogen:
Recombinant fragment of human SDHB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2251

Conjugate:
Unconjugated

Gene:
Sdhb

Gene Alias:
0710008N11Rik, CWS2, fj46d06, FLJ92337, I79_022285, Ip, iron-sulfur subunit, iron-sulfur subunit of complex II, OTTHUMP00000044624, PGL4, SDH, SDH1, SDH2, Sdhb, SDHB protein, SDHB, sdhB, SDHIP, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, succinate dehydrogenase complex iron sulfur subunit B, succinate dehydrogenase complex subunit B, succinate dehydrogenase complex subunit B, iron sulfur (Ip), succinate dehydrogenase complex, subunit B, iron sulfur (Ip), succinate dehydrogenase Ip subunit, succinate dehydrogenase iron-protein subunit, wu:fj46d06

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
298596, 6390, 67680

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550460

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Antigen:
RPLP2

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P02401, P05387, P99027

Gene Symbols:
RPLP2

Immunogen:
Recombinant fragment of human RPLP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2256

Conjugate:
Unconjugated

Gene:
RPLP2

Gene Alias:
2700049I22Rik, 60S acidic ribosomal protein P2, acidic ribosomal phosphoprotein P2, D11S2243E, L RP D11S2243E, Large ribosomal subunit protein P2, LP2, P2, Renal carcinoma antigen NY-REN-44, ribosomal protein lateral stalk subunit P2, ribosomal protein P2, ribosomal protein, large P2, ribosomal protein, large, P2, RP2, Rplp2, RPP2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
140662, 335629, 6181, 67186

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550463

--


Antigen:
CARD10

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P58660, Q9BWT7

Gene Symbols:
CARD10

Immunogen:
Recombinant fragment of human CARD10.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2260

Conjugate:
Unconjugated

Gene:
CARD10

Gene Alias:
AI449026, Bcl10 binding protein and activator of NFKB, bcl10-interacting MAGUK protein 1, Bimp1, Card10, CARD-containing MAGUK 3 protein, CARD-containing MAGUK protein 3, Carma 3, Carma3, caspase recruitment domain family member 10, caspase recruitment domain family, member 10, caspase recruitment domain-containing protein 10

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
105844, 29775

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG