FEMA550595

GSDMD Monoclonal Antibody (A8D7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550595-Each-of-1 In Stock ₹ 40,127.64

FEMA550595 - Each of 1

₹ 40,127.64

In Stock

Quantity

1

Base Price: ₹ 40,127.64

GST (18%): ₹ 7,222.975

Total Price: ₹ 47,350.615

Antigen

GSDMD

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P57764, Q9D8T2

Gene Symbols

GSDMD

Immunogen

Recombinant protein within human GSDMD aa 101-300/484.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

Western Blot

Clone

A8D7

Conjugate

Unconjugated

Gene

GSDMD

Gene Alias

1810036L03Rik, AW558049, DF5L, Dfna5l, FKSG10, gasdermin D, gasdermin domain containing 1, gasdermin domain-containing protein 1, Gasdermin-D, Gasdermin-D, C-terminal, Gasdermin-D, N-terminal, GSDMD, GSDMDC1, GSDMD-CT, GSDMD-NT, M2-4

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

69146, 79792

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • Positive control: PC-3 cell lysate, NIH/3T3 cell lysate, THP-1 cell lysate
  • Predicted band size: 53 kDa Subcellular Location: Cytosol, Inflammasome; Secreted, Cell membrane
  • GSDMD (gasdermin-D) promotes pyroptosis in response to microbial infection and danger signals
  • It is produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4 in response to canonical, as well as, non-canonical (such as cytosolic LPS) inflammasome activators
  • After cleavage, GSDMD moves to the plasma membrane where it strongly binds to inner leaflet lipids including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-biphosphate, phosphatidylinositol (3,4,5)-biphosphate, phosphatidic acid, and phosphatidylserine
  • GSDMD also exhibits bactericidal activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550595

--


Antigen:
GSDMD

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P57764, Q9D8T2

Gene Symbols:
GSDMD

Immunogen:
Recombinant protein within human GSDMD aa 101-300/484.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Western Blot

Clone:
A8D7

Conjugate:
Unconjugated

Gene:
GSDMD

Gene Alias:
1810036L03Rik, AW558049, DF5L, Dfna5l, FKSG10, gasdermin D, gasdermin domain containing 1, gasdermin domain-containing protein 1, Gasdermin-D, Gasdermin-D, C-terminal, Gasdermin-D, N-terminal, GSDMD, GSDMDC1, GSDMD-CT, GSDMD-NT, M2-4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
69146, 79792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

FEMA550596

--


Antigen:
GSDMD

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P57764

Gene Symbols:
GSDMD

Immunogen:
Recombinant protein within human GSDMD aa 101-300/484.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
A8D8

Conjugate:
Unconjugated

Gene:
GSDMD

Gene Alias:
1810036L03Rik, AW558049, DF5L, Dfna5l, FKSG10, gasdermin D, gasdermin domain containing 1, gasdermin domain-containing protein 1, Gasdermin-D, Gasdermin-D, C-terminal, Gasdermin-D, N-terminal, GSDMD, GSDMDC1, GSDMD-CT, GSDMD-NT, M2-4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

FEMA550597

--


Antigen:
IL-7

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P13232

Gene Symbols:
Il7

Immunogen:
Recombinant protein within human IL-7 aa 1-177/177.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
A8B11

Conjugate:
Unconjugated

Gene:
Il7

Gene Alias:
A630026I06Rik, H-IL-7, hlb368, IL7, Il-7, ILN, Interleukin, interleukin 7, Interleukin7, interleukin-7, M-IL-7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3574

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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FEMA550599

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Antigen:
IL-6

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P05231

Gene Symbols:
Il6

Immunogen:
Recombinant protein within human IL-6 aa 1-212/212.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
A6D2

Conjugate:
Unconjugated

Gene:
Il6

Gene Alias:
B-cell differentiation factor, B-cell hybridoma growth factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CHIL-6, CTL differentiation factor, cytokine, HGF, H-IL-6, HSF, hybridoma growth factor, Ifnb2, IFN-beta-2, Il6, IL-6, ILg6, ILN, interferon beta-2, Interleukin, interleukin 6, Interleukin 6 (interferon, beta 2), interleukin 6 precursor, interleukin BSF-2, interleukin HP-1, Interleukin6, Interleukin-6, interleukin-6 precursor, interleukin-6 protein, M-IL-6, prointerleukin 6, R-IL-6

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1