FEMA550642

PIEZO1 Recombinant Mouse Monoclonal Antibody (2-10-R-A), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 FEMA550642-Each-of-1 In Stock ₹ 40,641.00

FEMA550642 - Each of 1

₹ 40,641.00

In Stock

Quantity

1

Base Price: ₹ 40,641.00

GST (18%): ₹ 7,315.38

Total Price: ₹ 47,956.38

Antigen

PIEZO1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

E2JF22, Q0KL00, Q92508

Gene Symbols

Piezo1

Immunogen

Recombinant protein within Human Protein FAM38A aa 1275-1540/2521.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

2-10-R-A

Conjugate

Unconjugated

Gene

Piezo1

Gene Alias

9630020g22, DHS, Fam38a, family with sequence similarity 38, member A, KIAA0233, LMPH3, Membrane protein induced by beta-amyloid treatment, Mib, mKIAA0233, piezo type mechanosensitive ion channel component 1, Piezo1, piezo-type mechanosensitive ion channel component 1, Protein FAM38A, protein PIEZO1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

234839, 361430, 9780

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

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Description

  • Positive control: Recombinant protein lysates, rat brain tissue, mouse hippocampus tissue, mouse brain tissue
  • Predicted band size: 287 kDa Subcellular Location: Endoplasmic reticulum membrane Cell membrane
  • Piezo1 is a pore-forming subunit of a mechanosensitive non-specific cation channel, and generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium
  • Structurally, Piezo1 contains 36 transmembrane domains and functions as a homotetramer
  • Piezo1 plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling
  • In the kidney, Piezo1 may contribute to the detection of intraluminal pressure changes and to urine flow sensing
  • Piezo1 acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation and plays a key role in blood vessel formation and vascular structure in both development and adult physiology
  • The protein encoded by the Piezo1 gene is a mechanically-activated ion channel that links mechanical forces to biological signals
  • Defects in this gene have been associated with dehydrated hereditary stomatocytosis
  • Diseases associated with PIEZO1 include Dehydrated Hereditary Stomatocytosis with/without Pseudohyperkalemia And/Or Perinatal Edema and Lymphedema.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550642

--


Antigen:
PIEZO1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
E2JF22, Q0KL00, Q92508

Gene Symbols:
Piezo1

Immunogen:
Recombinant protein within Human Protein FAM38A aa 1275-1540/2521.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2-10-R-A

Conjugate:
Unconjugated

Gene:
Piezo1

Gene Alias:
9630020g22, DHS, Fam38a, family with sequence similarity 38, member A, KIAA0233, LMPH3, Membrane protein induced by beta-amyloid treatment, Mib, mKIAA0233, piezo type mechanosensitive ion channel component 1, Piezo1, piezo-type mechanosensitive ion channel component 1, Protein FAM38A, protein PIEZO1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
234839, 361430, 9780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

FEMA550643

--


Antigen:
ASS1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P00966, P09034, P16460

Gene Symbols:
ASS1

Immunogen:
Recombinant protein within Human ASS1 aa 1-412/412.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
11F1-RA

Conjugate:
Unconjugated

Gene:
ASS1

Gene Alias:
AA408052, arginino succinate synthetase, argininosuccinate synthase, argininosuccinate synthase 1, argininosuccinate synthetase, argininosuccinate synthetase 1, arginosuccinate synthetase 1, ASS, Ass1, Ass-1, ASSA, citrulline-aspartate ligase, citrulline--aspartate ligase, citrullinemia, CN, CTLN1, fold, mutant arginino succinate synthetase, RP11-618A20.2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11898, 25698, 445

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

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FEMA550645

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Antigen:
MSH2

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P43246, P43247, P54275

Gene Symbols:
Msh2

Immunogen:
Synthetic peptide within N-terminal residues of Human MSH2 aa 21-70/934.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
10G3-R

Conjugate:
Unconjugated

Gene:
Msh2

Gene Alias:
AI788990, COCA1, DNA mismatch repair protein MSH2, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, mismatch repair ATPase MSH2, mismatch repair protein, MSH2, Msh2p, mutS homolog 2, mutS homolog 2 (E. coli), mutS homolog 2, colon cancer, nonpolyposis type 1, mutS protein homolog 2, O0935, PMS5, YOL090W

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17685, 4436, 81709

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

FEMA550646

--


Antigen:
CD34

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P28906

Gene Symbols:
Cd34

Immunogen:
Synthetic peptide aa 336-385/385.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
PDM0-12

Conjugate:
Unconjugated

Gene:
Cd34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1, AU040960, CD34, CD34 antigen, CD34 molecule, CDC34, cell division cycle 34, cell division cycle 34 homolog, cluster designation 34, cluster of differentiation antigen 34, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, hematopoietic progenitor cell antigen CD34, hematopoietic progenitor cell marker CD34, Mucosialin, RP11-328D5.2, sialomucin protein, type 1 transmembrane protein, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
947

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1