FEMA550708
Mesothelin Recombinant Rabbit Monoclonal Antibody (PD00-68), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550708-Each-of-1 | In Stock | ₹ 40,641.00 |
FEMA550708 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,641.00
GST (18%): ₹ 7,315.38
Total Price: ₹ 47,956.38
Antigen
Mesothelin
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q13421
Gene Symbols
MSLN
Immunogen
Synthetic peptide within Human Mesothelin aa 550 to the C-terminus.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
PD00-68
Conjugate
Unconjugated
Gene
MSLN
Gene Alias
CAK1, CAK1 antigen, megakaryocyte potentiating factor, Megakaryocyte-potentiating factor, Mes, Mesothelin, Mesothelin, cleaved form, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor, SMR, SMRP, soluble MPF mesothelin related protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10232
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: HeLa cell lysate, SK-OV-3 cell lysate, OVCAR-3 cell lysate, SiHa cell lysate, NCI-H226 cell lysate, human tonsil tissue, human ovarian carcinoma tissue
- Predicted band size: 69 kDa Subcellular Location: Cell membrane, Golgi apparatus; Secreted
- Originally identified as a differentiation antigen of mesotheliomas, ovarian cystadenocarcinomas, and pancreatic adenocarcinomas, Mesothelin is a glycosylphosphatidylinositol (GPI)-anchored, cell-surface glycoprotein predominantly secreted by cells of the mesothelium
- Although Mesothelin is expressed at restricted levels by normal mesothelial cells of the pleural,pericardial, and peritoneal membranes, aberrant expression has been documented in the aforementioned cancers, as well as in endometriod uterine adenocarcinomas and squamous cell carcinomas of the esophagus, stomach, lung, and cervix
- Proteolytic cleavage of Mesothelin yields a soluble, polypeptide fragment designated megakaryocyte potentiating factor (MPF) based on its ability to stimulate megakaryocyte colony-forming activity of murine interleukin-3 in murine bone marrow cell cultures
- Originally isolated from the HPC-Y5 pancreatic cell line, MPF has been suggested to play a role in the proliferation and differentiation of megakaryoctyes, and the regulation of resultant platelet production
- While the biological functions of both Mesothelin and MPF remain speculative, high-levels of expression in cancerous tissues compared to limited distribution in normal tissues strongly suggests their involvement in tumorigenesis
- Both have been demonstrated to promote tumor cell proliferation, migration,anchorage-independent growth, and tumor progression; demonstrating their involvement in heterotypic cell adhesion and the metastatic spread of cancer.
Compare Similar Items
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Antigen: Mesothelin
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q13421
Gene Symbols: MSLN
Immunogen: Synthetic peptide within Human Mesothelin aa 550 to the C-terminus.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: PD00-68
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1, CAK1 antigen, megakaryocyte potentiating factor, Megakaryocyte-potentiating factor, Mes, Mesothelin, Mesothelin, cleaved form, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor, SMR, SMRP, soluble MPF mesothelin related protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 10232
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Mesothelin
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q13421
Gene Symbols:
MSLN
Immunogen:
Synthetic peptide within Human Mesothelin aa 550 to the C-terminus.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
PD00-68
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1, CAK1 antigen, megakaryocyte potentiating factor, Megakaryocyte-potentiating factor, Mes, Mesothelin, Mesothelin, cleaved form, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor, SMR, SMRP, soluble MPF mesothelin related protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
10232
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: Stathmin 1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P16949
Gene Symbols: Stmn1
Immunogen: Synthetic peptide within Human Stathmin 1 aa 100 to the C-terminus (internal sequence).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: PD00-54
Conjugate: Unconjugated
Gene: Stmn1
Gene Alias: 19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3925
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Stathmin 1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P16949
Gene Symbols:
Stmn1
Immunogen:
Synthetic peptide within Human Stathmin 1 aa 100 to the C-terminus (internal sequence).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
PD00-54
Conjugate:
Unconjugated
Gene:
Stmn1
Gene Alias:
19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3925
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: CSF1R
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P07333
Gene Symbols: Csf1r
Immunogen: Recombinant protein within human CSF1R aa 539-972/972 (Cytoplasmic)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: PD00-45
Conjugate: Unconjugated
Gene: Csf1r
Gene Alias: AI323359, CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog, CSF-1 receptor, CSF1R, CSF-1R, CSF-1-R, CSFIR, Csfmr, CSFR, EC 2.7.10.1, FIM2, Fim-2, FMS, fms proto-oncogene, HDLS, kinase CSFR, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, M-CSFR, M-CSF-R, mrfms, OTTHUMP00000224093, protein-tyrosine kinase, proto-oncogene c-Fms, proto-oncogene fms
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1436
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
CSF1R
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P07333
Gene Symbols:
Csf1r
Immunogen:
Recombinant protein within human CSF1R aa 539-972/972 (Cytoplasmic)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
PD00-45
Conjugate:
Unconjugated
Gene:
Csf1r
Gene Alias:
AI323359, CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog, CSF-1 receptor, CSF1R, CSF-1R, CSF-1-R, CSFIR, Csfmr, CSFR, EC 2.7.10.1, FIM2, Fim-2, FMS, fms proto-oncogene, HDLS, kinase CSFR, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, M-CSFR, M-CSF-R, mrfms, OTTHUMP00000224093, protein-tyrosine kinase, proto-oncogene c-Fms, proto-oncogene fms
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1436
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: Calcitonin
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P01258, P06881
Gene Symbols: CALCA
Immunogen: Synthetic peptide within human Calcitonin aa 85-116/141.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: PD00-46
Conjugate: Unconjugated
Gene: CALCA
Gene Alias: Alpha CGRP, Alpha type CGRP, Alpha-type CGRP, CA, Cal1, CAL6, CALC, CALC1, Calca, Calcitonin, calcitonin 1, Calcitonin carboxyl-terminal peptide, calcitonin gene related peptide 1, calcitonin gene related peptide I, calcitonin gene related peptide I precursor, Calcitonin gene-related peptide, calcitonin gene-related peptide 1, Calcitonin gene-related peptide I, calcitonin precursor, calcitonin related polypeptide alpha, calcitonin/calcitonin-related polypeptide, alpha, calcitonin, calcitonin gene-related peptide 1, calcitonin-like, calcitonin-related polypeptide alpha, CCALCI, CCP, Cgrp, CGRP1, CGRP-1, CGRPI, CGRP-I, CT, Ctn, katacalcin, katacalcin (KC), KC, PCT, PDN-21, prepro-alpha-calcitonin gene-related peptide, procalcitonin, RATCAL6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 796
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Calcitonin
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P01258, P06881
Gene Symbols:
CALCA
Immunogen:
Synthetic peptide within human Calcitonin aa 85-116/141.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
PD00-46
Conjugate:
Unconjugated
Gene:
CALCA
Gene Alias:
Alpha CGRP, Alpha type CGRP, Alpha-type CGRP, CA, Cal1, CAL6, CALC, CALC1, Calca, Calcitonin, calcitonin 1, Calcitonin carboxyl-terminal peptide, calcitonin gene related peptide 1, calcitonin gene related peptide I, calcitonin gene related peptide I precursor, Calcitonin gene-related peptide, calcitonin gene-related peptide 1, Calcitonin gene-related peptide I, calcitonin precursor, calcitonin related polypeptide alpha, calcitonin/calcitonin-related polypeptide, alpha, calcitonin, calcitonin gene-related peptide 1, calcitonin-like, calcitonin-related polypeptide alpha, CCALCI, CCP, Cgrp, CGRP1, CGRP-1, CGRPI, CGRP-I, CT, Ctn, katacalcin, katacalcin (KC), KC, PCT, PDN-21, prepro-alpha-calcitonin gene-related peptide, procalcitonin, RATCAL6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
796
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG