FEMA550715
Phospho-CHK1 (Ser345) Recombinant Rabbit Monoclonal Antibody (PS01-17), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550715-Each-of-1 | In Stock | ₹ 40,641.00 |
FEMA550715 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,641.00
GST (18%): ₹ 7,315.38
Total Price: ₹ 47,956.38
Antigen
Phospho-CHK1 (Ser345)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O14757
Gene Symbols
Chek1
Immunogen
Synthetic peptide surrounding Ser345 of human Chk1/476.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Clone
PS01-17
Conjugate
Unconjugated
Gene
Chek1
Gene Alias
C85740, Cell cycle checkpoint kinase, checkpoint kinase 1, checkpoint kinase 1 homolog, checkpoint kinase-1, Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog, Chk1-S, homolog of Chk1-S, HRD1 Protein, rad27, rad27 homolog, serine/threonine protein kinase CHK1, serine/threonine-protein kinase Chk1, Synoviolin, YBR1742, YBR274W
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1111
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: HeLa treated with Etoposide cell lysate, HeLa treated with Hydroxyurea cell lysate, HeLa treated with 4mM Hydroxyurea for 20 hours
- Predicted band size: 54 kDa Subcellular Location: Nucleus, Chromosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Phospho-CHK1 (Ser345)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O14757
Gene Symbols: Chek1
Immunogen: Synthetic peptide surrounding Ser345 of human Chk1/476.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: PS01-17
Conjugate: Unconjugated
Gene: Chek1
Gene Alias: C85740, Cell cycle checkpoint kinase, checkpoint kinase 1, checkpoint kinase 1 homolog, checkpoint kinase-1, Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog, Chk1-S, homolog of Chk1-S, HRD1 Protein, rad27, rad27 homolog, serine/threonine protein kinase CHK1, serine/threonine-protein kinase Chk1, Synoviolin, YBR1742, YBR274W
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1111
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Phospho-CHK1 (Ser345)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O14757
Gene Symbols:
Chek1
Immunogen:
Synthetic peptide surrounding Ser345 of human Chk1/476.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
PS01-17
Conjugate:
Unconjugated
Gene:
Chek1
Gene Alias:
C85740, Cell cycle checkpoint kinase, checkpoint kinase 1, checkpoint kinase 1 homolog, checkpoint kinase-1, Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog, Chk1-S, homolog of Chk1-S, HRD1 Protein, rad27, rad27 homolog, serine/threonine protein kinase CHK1, serine/threonine-protein kinase Chk1, Synoviolin, YBR1742, YBR274W
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1111
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: eIF4E
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06730, P63073
Gene Symbols: Eif4e
Immunogen: Recombinant protein within Human eIF4E aa 118-217/217.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: JE60-70
Conjugate: Unconjugated
Gene: Eif4e
Gene Alias: AUTS19, CBP, EG668879, EIF4E, EIF-4E, EIF4E1, EIF4EL1, Eif4e-ps, EIF4F, eIF-4F 25 kDa subunit, eukaryotic translation initiation factor 4E, eukaryotic translation initiation factor 4E-like 1, eukaryotic translation initiation factor 4E-like protein, eukaryotic translation initiation factor 4-like protein, If4e, MGC111573, mRNA cap-binding protein, OTTHUMP00000219703, OTTHUMP00000219704, OTTHUMP00000219705, translation initiation factor eIF-4E
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 13684, 1977
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
eIF4E
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P06730, P63073
Gene Symbols:
Eif4e
Immunogen:
Recombinant protein within Human eIF4E aa 118-217/217.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
JE60-70
Conjugate:
Unconjugated
Gene:
Eif4e
Gene Alias:
AUTS19, CBP, EG668879, EIF4E, EIF-4E, EIF4E1, EIF4EL1, Eif4e-ps, EIF4F, eIF-4F 25 kDa subunit, eukaryotic translation initiation factor 4E, eukaryotic translation initiation factor 4E-like 1, eukaryotic translation initiation factor 4E-like protein, eukaryotic translation initiation factor 4-like protein, If4e, MGC111573, mRNA cap-binding protein, OTTHUMP00000219703, OTTHUMP00000219704, OTTHUMP00000219705, translation initiation factor eIF-4E
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
13684, 1977
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: delta Catenin
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O60716
Gene Symbols: CTNND1
Immunogen: Synthetic peptide within Human delta 1 Catenin/CAS aa 850-950/968.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: PD00-43
Conjugate: Unconjugated
Gene: CTNND1
Gene Alias: AA409437, AU019353, cadherin-associated Src substrate, Cadherin-associated Src substrate (CAS), CAS, Catenin (cadherin associated protein) delta 1, catenin (cadherin associated protein), delta 1, catenin (cadherin-associated protein), delta 1, catenin delta 1, catenin delta-1, catenin src, catenin, delta 1, Catns, CTNND, Ctnnd1, hypothetical protein, Kiaa0384, mKIAA0384, p120, p120 catenin, P120 CTN, P120 p120, P120 P120CTN, p120(CAS), p120(ctn), P120CAS, p120-catenin, P120CTN
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1500
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
delta Catenin
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O60716
Gene Symbols:
CTNND1
Immunogen:
Synthetic peptide within Human delta 1 Catenin/CAS aa 850-950/968.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
PD00-43
Conjugate:
Unconjugated
Gene:
CTNND1
Gene Alias:
AA409437, AU019353, cadherin-associated Src substrate, Cadherin-associated Src substrate (CAS), CAS, Catenin (cadherin associated protein) delta 1, catenin (cadherin associated protein), delta 1, catenin (cadherin-associated protein), delta 1, catenin delta 1, catenin delta-1, catenin src, catenin, delta 1, Catns, CTNND, Ctnnd1, hypothetical protein, Kiaa0384, mKIAA0384, p120, p120 catenin, P120 CTN, P120 p120, P120 P120CTN, p120(CAS), p120(ctn), P120CAS, p120-catenin, P120CTN
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1500
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: FOXP1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q9H334
Gene Symbols: FOXP1
Immunogen: Synthetic peptide within Human FOXP1 aa 350-450/677.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: PD00-47
Conjugate: Unconjugated
Gene: FOXP1
Gene Alias: 12CC4, 3110052D19Rik, 4932443N09Rik, AI461938, AW494214, FLJ23741, Fork head related protein like B, fork head-related protein like B, forkhead box P1, forkhead box protein P1, Forkhead box protein P1 (FOXP1), Forkhead-related transcription factor 1, Foxp1, Glutamine rich factor 1, glutamine-rich factor 1, hFKH1B, HSPC215, mac-1-regulated forkhead, MFH, MGC12942, MGC88572, MGC99551, QRF1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 27086
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
FOXP1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q9H334
Gene Symbols:
FOXP1
Immunogen:
Synthetic peptide within Human FOXP1 aa 350-450/677.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
PD00-47
Conjugate:
Unconjugated
Gene:
FOXP1
Gene Alias:
12CC4, 3110052D19Rik, 4932443N09Rik, AI461938, AW494214, FLJ23741, Fork head related protein like B, fork head-related protein like B, forkhead box P1, forkhead box protein P1, Forkhead box protein P1 (FOXP1), Forkhead-related transcription factor 1, Foxp1, Glutamine rich factor 1, glutamine-rich factor 1, hFKH1B, HSPC215, mac-1-regulated forkhead, MFH, MGC12942, MGC88572, MGC99551, QRF1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
27086
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG