FEMA550815

MLH1 Recombinant Rabbit Monoclonal Antibody (PD01-61), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 FEMA550815-Each-of-1 In Stock ₹ 40,641.00

FEMA550815 - Each of 1

₹ 40,641.00

In Stock

Quantity

1

Base Price: ₹ 40,641.00

GST (18%): ₹ 7,315.38

Total Price: ₹ 47,956.38

Antigen

MLH1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P40692, P97679

Gene Symbols

Mlh1

Immunogen

Synthetic peptide corresponding to Human MLH1 aa 700-756/756.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

PD01-61

Conjugate

Unconjugated

Gene

Mlh1

Gene Alias

1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4292, 81685

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Positive control: K562 cell lysates, human colon tissue, rat small intestine tissue, human colon carcinoma tissue, human tonsil tissue
  • Predicted band size: 85 kDa Subcellular Location: Nucleus
  • MLH1 is a DNA mismatch repair protein
  • The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
  • An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
  • These defects in DNA repair pathways have been related to human carcinogenesis
  • The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
  • MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550815

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Antigen:
MLH1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P40692, P97679

Gene Symbols:
Mlh1

Immunogen:
Synthetic peptide corresponding to Human MLH1 aa 700-756/756.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
PD01-61

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4292, 81685

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550816

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Antigen:
GNAQ

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P21279, P50148, P82471

Gene Symbols:
GNAQ

Immunogen:
Recombinant protein within Human GNAQ aa 51-150/359.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
JE65-59

Conjugate:
Unconjugated

Gene:
GNAQ

Gene Alias:
1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, G alpha q, G protein subunit alpha q, Galpha q, Galphaq, G-ALPHA-q, GAQ, GNAQ, gnaqa, Gq, GqI, guanine nucleotide binding protein (G protein), q polypeptide, guanine nucleotide binding protein alpha q subunit, guanine nucleotide binding protein, alpha q polypeptide, guanine nucleotide regulatory protein G alpha q, guanine nucleotide-binding protein alpha-q, Guanine nucleotide-binding protein G(q) subunit alpha, heterotrimeric guanine nucleotide-binding protein alpha q subunit, si:ch73-270f14.2, SWS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14682, 2776, 81666

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

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FEMA550817

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Antigen:
FDX1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P10109, P24483, P46656

Gene Symbols:
FDX1

Immunogen:
Synthetic peptide within Human ADX aa 51-100/184.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JE63-56

Conjugate:
Unconjugated

Gene:
FDX1

Gene Alias:
adrenal ferredoxin, Adrenodoxin, mitochondrial, ADX, FDX, Fdx1, ferredoxin 1, ferredoxin-1, Hepatoredoxin, LOH11CR1D, mitochondrial adrenodoxin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14148, 2230, 29189

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

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FEMA550820

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Antigen:
LYPD3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O95274

Gene Symbols:
LYPD3

Immunogen:
Synthetic peptide aa 1-346/346.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
PS00-59

Conjugate:
Unconjugated

Gene:
LYPD3

Gene Alias:
2310061G07Rik, C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog, GPI-anchored metastasis-associated protein homolog, LY6/PLAUR domain containing 3, ly6/PLAUR domain-containing protein 3, LYPD3, Matrigel-induced gene C4 protein, MIG-C4, UNQ491/PRO1007

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27076

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG