FEMA550962

RIP1 Monoclonal Antibody (C4), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550962-Each-of-1 In Stock ₹ 15,640.37

FEMA550962 - Each of 1

₹ 15,640.37

In Stock

Quantity

1

Base Price: ₹ 15,640.37

GST (18%): ₹ 2,815.267

Total Price: ₹ 18,455.637

Antigen

RIP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

Q13546

Gene Symbols

RIPK1

Immunogen

Recombinant Human RIPK1 protein, Phe17-Tyr289 (Accession #Q13546)

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C4

Conjugate

Unconjugated

Gene

RIPK1

Gene Alias

cell death protein RIP, D330015H01Rik, FLJ39204, OTTHUMP00000015955, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting serine/threonine kinase 1, receptor-interacting protein 1, receptor-interacting protein kinase 1, receptor-interacting serine/threonine-protein kinase 1, Rinp, RIP, RIP1, RIP-1, RIP1 (CT), RIPK1, serine/threonine-protein kinase RIP

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

100524751, 8737

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b κ

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Description

  • Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
  • Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
  • Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
  • Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
  • Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
  • Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
  • RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.

Compare Similar Items

Show Difference

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Fischer Scientific

FEMA550962

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Antigen:
RIP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q13546

Gene Symbols:
RIPK1

Immunogen:
Recombinant Human RIPK1 protein, Phe17-Tyr289 (Accession #Q13546)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C4

Conjugate:
Unconjugated

Gene:
RIPK1

Gene Alias:
cell death protein RIP, D330015H01Rik, FLJ39204, OTTHUMP00000015955, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting serine/threonine kinase 1, receptor-interacting protein 1, receptor-interacting protein kinase 1, receptor-interacting serine/threonine-protein kinase 1, Rinp, RIP, RIP1, RIP-1, RIP1 (CT), RIPK1, serine/threonine-protein kinase RIP

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100524751, 8737

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA550963

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Antigen:
Lamin B1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P20700

Gene Symbols:
Lmnb1

Immunogen:
Recombinant Human LMNB1 protein, Ser52-Gly233 (Accession #P20700)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Rabbit

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C4

Conjugate:
Unconjugated

Gene:
Lmnb1

Gene Alias:
0710005A05Rik, ADLD, C-flanking peptide of NPY, CPON, fc06g01, I79_003938, lamin B1, lamin B1 L homeolog, lamin B1 protein, lamin-b, lamin-B1, Lamin-L(I), LMN, LMN2, LMNB, LMNB1, lmnb1 protein, lmnb1.L, MGC111419, Neuropeptide tyrosine, Neuropeptide Y, NPY, NPY02, prepro-neuropeptide Y, pro-neuropeptide Y, PYY4, RATNPY, RATNPY02, unnamed protein product, wu:fc06g01, XELAEV_18007951mg

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100346094, 4001

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA550964

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Antigen:
Lamin B1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P20700

Gene Symbols:
Lmnb1

Immunogen:
Recombinant Human LMNB1 protein, Ser52-Gly233 (Accession #P20700)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Rabbit

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C4

Conjugate:
Unconjugated

Gene:
Lmnb1

Gene Alias:
0710005A05Rik, ADLD, C-flanking peptide of NPY, CPON, fc06g01, I79_003938, lamin B1, lamin B1 L homeolog, lamin B1 protein, lamin-b, lamin-B1, Lamin-L(I), LMN, LMN2, LMNB, LMNB1, lmnb1 protein, lmnb1.L, MGC111419, Neuropeptide tyrosine, Neuropeptide Y, NPY, NPY02, prepro-neuropeptide Y, pro-neuropeptide Y, PYY4, RATNPY, RATNPY02, unnamed protein product, wu:fc06g01, XELAEV_18007951mg

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100346094, 4001

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA550965

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Antigen:
PCSK9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P59996

Gene Symbols:
PCSK9

Immunogen:
Recombinant Rat PCSK9 protein, Trp164-Phe428 (Accession #P59996)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C5

Conjugate:
Unconjugated

Gene:
PCSK9

Gene Alias:
AI415265, AI747682, convertase subtilisin, convertase subtilisin/kexin type 9 preproprotein, FH3, HCHOLA3, hypercholesterolemia, LDLCQ1, NARC1, NARC-1, neural apoptosis regulated convertase 1, neural apoptosis-regulated convertase 1, OTTHUMP00000009833, PC9, PCSK9, Proprotein convertase 9, proprotein convertase PC9, proprotein convertase subtilisin/kexin type 9, PSEC0052, Subtilisin/kexin-like protease PC9

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
298296

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ