FEMA550997

Nephrin Monoclonal Antibody (C14), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550997-Each-of-1 In Stock ₹ 32,256.12

FEMA550997 - Each of 1

₹ 32,256.12

In Stock

Quantity

1

Base Price: ₹ 32,256.12

GST (18%): ₹ 5,806.102

Total Price: ₹ 38,062.222

Antigen

Nephrin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

O60500, Q9QZS7, Q9R044

Gene Symbols

Nphs1

Immunogen

Recombinant Human NPHN protein, Arg1160-Val1241 (Accession #O60500)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C14

Conjugate

Unconjugated

Gene

Nphs1

Gene Alias

CNF, Nephrin, nephrin 1, NephrinB, nephrosis 1 homolog, nephrin, nephrosis 1, congenital, Finnish type (nephrin), nephrosis 1, nephrin, NPHN, NPHS1, NPHS1 nephrin, NPHS1, nephrin, renal glomerulus-specific cell adhesion receptor

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

4868, 54631, 64563

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b κ

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Description

  • Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
  • Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
  • Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
  • Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
  • Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
  • Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
  • Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
  • The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
  • Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.

Compare Similar Items

Show Difference

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Fischer Scientific

FEMA550997

--


Antigen:
Nephrin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
O60500, Q9QZS7, Q9R044

Gene Symbols:
Nphs1

Immunogen:
Recombinant Human NPHN protein, Arg1160-Val1241 (Accession #O60500)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C14

Conjugate:
Unconjugated

Gene:
Nphs1

Gene Alias:
CNF, Nephrin, nephrin 1, NephrinB, nephrosis 1 homolog, nephrin, nephrosis 1, congenital, Finnish type (nephrin), nephrosis 1, nephrin, NPHN, NPHS1, NPHS1 nephrin, NPHS1, nephrin, renal glomerulus-specific cell adhesion receptor

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
4868, 54631, 64563

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA550998

--


Antigen:
Nephrin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
O60500, Q9QZS7, Q9R044

Gene Symbols:
Nphs1

Immunogen:
Recombinant Human NPHN protein, Arg1160-Val1241 (Accession #O60500)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C14

Conjugate:
Unconjugated

Gene:
Nphs1

Gene Alias:
CNF, Nephrin, nephrin 1, NephrinB, nephrosis 1 homolog, nephrin, nephrosis 1, congenital, Finnish type (nephrin), nephrosis 1, nephrin, NPHN, NPHS1, NPHS1 nephrin, NPHS1, nephrin, renal glomerulus-specific cell adhesion receptor

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
4868, 54631, 64563

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA551001

--


Antigen:
HRG

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q99PS8

Gene Symbols:
HRG

Immunogen:
Recombinant Eukaryotic Rat HRG protein, Leu19-Lys525 (Accession #Q99PS8)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C4

Conjugate:
Unconjugated

Gene:
HRG

Gene Alias:
AI265597, AW413091, D16jh2, D18020, DKFZp779H1622, histidine rich glycoprotein, histidine-proline-rich glycoprotein, Histidine-rich glycoprotein, histidine-rich glycoprotein 1, HPRG, HRG, HRG1, Hrgp, THPH11

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
171016

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA551002

--


Antigen:
HRG

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q99PS8

Gene Symbols:
HRG

Immunogen:
Recombinant Eukaryotic Rat HRG protein, Leu19-Lys525 (Accession #Q99PS8)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C4

Conjugate:
Unconjugated

Gene:
HRG

Gene Alias:
AI265597, AW413091, D16jh2, D18020, DKFZp779H1622, histidine rich glycoprotein, histidine-proline-rich glycoprotein, Histidine-rich glycoprotein, histidine-rich glycoprotein 1, HPRG, HRG, HRG1, Hrgp, THPH11

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
171016

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ