FEMA551024

CD22 Monoclonal Antibody (C2), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551024-Each-of-1 In Stock ₹ 15,640.37

FEMA551024 - Each of 1

₹ 15,640.37

In Stock

Quantity

1

Base Price: ₹ 15,640.37

GST (18%): ₹ 2,815.267

Total Price: ₹ 18,455.637

Antigen

CD22

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P20273

Gene Symbols

CD22

Immunogen

Recombinant Human CD22 protein, His28-Ile246 (Accession #P20273)

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C2

Conjugate

Unconjugated

Gene

CD22

Gene Alias

A530093D23, B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, B-lymphocyte cell adhesion molecule (BL-CAM), Cd22, CD22 antigen, CD22 molecule, FLJ22814, Lectin 2, Leu-14, Lyb8, Lyb-8, MGC130020, sialic acid binding Ig-like lectin 2, sialic acid-binding Ig-like lectin 2, Sialic acid-binding Ig-like lectin 2 (Siglec-2), Siglec2, Siglec-2, T-cell surface antigen Leu-14

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

933

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.

Compare Similar Items

Show Difference

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Fischer Scientific

FEMA551024

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Antigen:
CD22

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
Recombinant Human CD22 protein, His28-Ile246 (Accession #P20273)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C2

Conjugate:
Unconjugated

Gene:
CD22

Gene Alias:
A530093D23, B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, B-lymphocyte cell adhesion molecule (BL-CAM), Cd22, CD22 antigen, CD22 molecule, FLJ22814, Lectin 2, Leu-14, Lyb8, Lyb-8, MGC130020, sialic acid binding Ig-like lectin 2, sialic acid-binding Ig-like lectin 2, Sialic acid-binding Ig-like lectin 2 (Siglec-2), Siglec2, Siglec-2, T-cell surface antigen Leu-14

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

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FEMA551027

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Antigen:
Calponin 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q08094, Q99439

Gene Symbols:
Cnn2

Immunogen:
Recombinant Human CNN2 protein, Met1-Tyr269 (Accession #Q99439)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C8

Conjugate:
Unconjugated

Gene:
Cnn2

Gene Alias:
AA408047, AI324678, Calpo2, calponin 2, calponin H2, smooth muscle, Calponin-2, CLP2, CNN2, h2-calponin, LOW QUALITY PROTEIN: calponin-2, neutral calponin

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1265, 397565

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

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FEMA551028

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Antigen:
Calponin 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q08094, Q99439

Gene Symbols:
Cnn2

Immunogen:
Recombinant Human CNN2 protein, Met1-Tyr269 (Accession #Q99439)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C8

Conjugate:
Unconjugated

Gene:
Cnn2

Gene Alias:
AA408047, AI324678, Calpo2, calponin 2, calponin H2, smooth muscle, Calponin-2, CLP2, CNN2, h2-calponin, LOW QUALITY PROTEIN: calponin-2, neutral calponin

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1265, 397565

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

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FEMA551029

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Antigen:
S100A9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P06702

Gene Symbols:
S100A9

Immunogen:
Recombinant Human S100A9 protein, Met1-Pro114 (Accession #P06702)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
H5

Conjugate:
Unconjugated

Gene:
S100A9

Gene Alias:
60B8AG, AW546964, BEE22, BM-009, Cagb, calgranulin B, calgranulin-B, Calprotectin L1H subunit, CFAG, CGLB, DKFZp686B04128, GAGB, intracellular calcium-binding protein (MRP14), L1AG, Leukocyte L1 complex heavy chain, LIAG, MAC387, Macrophage, MIF, Migration inhibitory factor-related protein 14, Monocyte, MRP14, MRP-14, MRP15, MRP16, myeloid-related protein 14, NIF, P14, protein S100-A9, S100 A9, S100 calcium binding protein A9, S100 calcium binding protein A9 (calgranulin B), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B), S100a9

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100127489, 6280

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ