FEMA551069

Laminin gamma-2 Monoclonal Antibody (D1), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551069-Each-of-1 In Stock ₹ 35,764.08

FEMA551069 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Laminin gamma-2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

Q13753

Gene Symbols

Lamc2

Immunogen

Recombinant Human LAMC2 protein, Cys28-Cys196 (Accession #Q13753)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

D1

Conjugate

Unconjugated

Gene

Lamc2

Gene Alias

AA589349, alternatively spliced laminin gamma2 chain, B2T, BM600, BM600-100kDa, cell-scattering factor 140 kDa subunit, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, ladsin 140 kDa subunit, LAM LAMNB2, LAMB2T, LAMC2, lamimin, gamma 2, laminin B2t chain, laminin gamma2 chain, laminin subunit gamma 2, laminin subunit gamma-2, laminin, gamma 2, laminin-5 subunit gamma, LAMNB2, Large adhesive scatter factor 140 kDa subunit, nicein subunit gamma, nicein, 100kD, nicein, 100kDa

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3918

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes
  • They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis
  • Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains
  • Each laminin chain is a multidomain protein encoded by a distinct gene
  • Several isoforms of each chain have been described
  • Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e
  • alpha1beta1gamma1 heterotrimer is laminin 1
  • The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo
  • This gene encodes the gamma chain isoform laminin, gamma 2
  • The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain; however, it lacks domain VI, and domains V, IV and III are shorter
  • It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney
  • The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane
  • The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction
  • Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described
  • The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known
  • Transcript variants utilizing alternative polyA_signal have also been noted in literature.

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Show Difference

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Fischer Scientific

FEMA551069

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Antigen:
Laminin gamma-2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q13753

Gene Symbols:
Lamc2

Immunogen:
Recombinant Human LAMC2 protein, Cys28-Cys196 (Accession #Q13753)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D1

Conjugate:
Unconjugated

Gene:
Lamc2

Gene Alias:
AA589349, alternatively spliced laminin gamma2 chain, B2T, BM600, BM600-100kDa, cell-scattering factor 140 kDa subunit, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, ladsin 140 kDa subunit, LAM LAMNB2, LAMB2T, LAMC2, lamimin, gamma 2, laminin B2t chain, laminin gamma2 chain, laminin subunit gamma 2, laminin subunit gamma-2, laminin, gamma 2, laminin-5 subunit gamma, LAMNB2, Large adhesive scatter factor 140 kDa subunit, nicein subunit gamma, nicein, 100kD, nicein, 100kDa

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3918

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Fischer Scientific

FEMA551070

--


Antigen:
Laminin gamma-2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q13753

Gene Symbols:
Lamc2

Immunogen:
Recombinant Human LAMC2 protein, Cys28-Cys196 (Accession #Q13753)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D1

Conjugate:
Unconjugated

Gene:
Lamc2

Gene Alias:
AA589349, alternatively spliced laminin gamma2 chain, B2T, BM600, BM600-100kDa, cell-scattering factor 140 kDa subunit, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, ladsin 140 kDa subunit, LAM LAMNB2, LAMB2T, LAMC2, lamimin, gamma 2, laminin B2t chain, laminin gamma2 chain, laminin subunit gamma 2, laminin subunit gamma-2, laminin, gamma 2, laminin-5 subunit gamma, LAMNB2, Large adhesive scatter factor 140 kDa subunit, nicein subunit gamma, nicein, 100kD, nicein, 100kDa

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3918

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

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FEMA551071

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Antigen:
GC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P02774

Gene Symbols:
GC

Immunogen:
Recombinant Human DBP protein, Leu209-Asp401 (Accession #P02774)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D4

Conjugate:
Unconjugated

Gene:
GC

Gene Alias:
DBP, DBP/ VDBG, DBP/GC, DBP02, DBP-maf, epididymis secretory protein Li 51, Gc, Gc globulin, Gc protein-derived macrophage activating factor, GC, vitamin D binding protein, gc-globulin, GcMAF, Gc-MAF, GRD3, group specific component, Group specific component vitamin D binding protein, Group-specific component, group-specific component (vitamin D binding protein), hDBP, HEL-S-51, V VDB, VDB, VDBG, Vdbp, Vitamin D binding alpha globulin, vitamin D-binding alpha-globulin, vitamin D-binding protein, Vitamin D-binding protein-macrophage activating factor

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
2638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

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FEMA551072

--


Antigen:
GC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P02774

Gene Symbols:
GC

Immunogen:
Recombinant Human DBP protein, Leu209-Asp401 (Accession #P02774)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D4

Conjugate:
Unconjugated

Gene:
GC

Gene Alias:
DBP, DBP/ VDBG, DBP/GC, DBP02, DBP-maf, epididymis secretory protein Li 51, Gc, Gc globulin, Gc protein-derived macrophage activating factor, GC, vitamin D binding protein, gc-globulin, GcMAF, Gc-MAF, GRD3, group specific component, Group specific component vitamin D binding protein, Group-specific component, group-specific component (vitamin D binding protein), hDBP, HEL-S-51, V VDB, VDB, VDBG, Vdbp, Vitamin D binding alpha globulin, vitamin D-binding alpha-globulin, vitamin D-binding protein, Vitamin D-binding protein-macrophage activating factor

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
2638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ