FEPA5144098

LCK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144098-Each-of-1 In Stock ₹ 30,544.92

FEPA5144098 - Each of 1

₹ 30,544.92

In Stock

Quantity

1

Base Price: ₹ 30,544.92

GST (18%): ₹ 5,498.086

Total Price: ₹ 36,043.006

Antigen

LCK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LCK

Gene Alias

EC 2.7.10.2, Hck-3, IMD22, kinase Lck, Lck, LCK proto-oncogene, Src family tyrosine kinase, Lck1, Lcktkr, leukocyte C-terminal Src kinase, LSK, Lskt, Lsk-t, Lymphocyte cell-specific protein-tyrosine kinase, lymphocyte protein tyrosine kinase, lymphocyte-specific protein tyrosine kinase, OTTHUMP00000008640, OTTHUMP00000008740, OTTHUMP00000008741, p56(LSTRA) protein-tyrosine kinase, p56<lck>, p56lck, p56-LCK, pp58lck, Protein YT16, Proto-oncogene Lck, Proto-oncogene tyrosine-protein kinase LCK, RP4-675E8.4, t cell-specific protein-tyrosine kinase, T-lymphocyte specific protein tyrosine kinase p56lck, tyr, tyrosine-protein kinase Lck, YT16

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3932

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration

5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.

P06239

Gene Symbols

LCK

Immunogen

Recombinant Human Tyrosine-protein kinase Lck protein (1-539AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Description

  • LCK is a member of the Src-family tyrosine kinase, which are essential for signaling through the T-cell receptor (TCR) complex
  • Upon TCR triggering, LCK phosphorylates the ITAM motives in its zeta subunits establishing binding sites for the SH2 domains of the tyrosine kinase ZAP70, which is also phosphorylated by LCK and activated to generate subsequent signaling platforms by phosphorylation of adaptor LAT
  • The majority of LCK is localized to the plasma membrane, however, there is also a significant fraction associated with the Golgi apparatus which may contribute to Raf activation under conditions of weak stimulation through the TCR
  • LCK contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively
  • LCK is also involved in the regulation of apoptosis induced by various stimuli, but not by the death receptors
  • Diseases associated with LCK include Immunodeficiency 22 and CD45 deficiency
  • Alternatively splice variants of the LCK gene encoding different isoforms of the protein have been found.

Compare Similar Items

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Img

Thermo Scientific

FEPA5144098

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Antigen:
LCK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCK

Gene Alias:
EC 2.7.10.2, Hck-3, IMD22, kinase Lck, Lck, LCK proto-oncogene, Src family tyrosine kinase, Lck1, Lcktkr, leukocyte C-terminal Src kinase, LSK, Lskt, Lsk-t, Lymphocyte cell-specific protein-tyrosine kinase, lymphocyte protein tyrosine kinase, lymphocyte-specific protein tyrosine kinase, OTTHUMP00000008640, OTTHUMP00000008740, OTTHUMP00000008741, p56(LSTRA) protein-tyrosine kinase, p56<lck>, p56lck, p56-LCK, pp58lck, Protein YT16, Proto-oncogene Lck, Proto-oncogene tyrosine-protein kinase LCK, RP4-675E8.4, t cell-specific protein-tyrosine kinase, T-lymphocyte specific protein tyrosine kinase p56lck, tyr, tyrosine-protein kinase Lck, YT16

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3932

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration:
5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P06239

Gene Symbols:
LCK

Immunogen:
Recombinant Human Tyrosine-protein kinase Lck protein (1-539AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144099

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Antigen:
LY6H

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LY6H

Gene Alias:
LY6H, Ly-6H, lymphocyte antigen 6 complex, locus H, lymphocyte antigen 6H, NMLY6

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4062

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
3.155 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
O94772

Gene Symbols:
LY6H

Immunogen:
Recombinant Human Lymphocyte antigen 6H protein (26-115AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

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FEPA5144100

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Antigen:
MYADM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYADM

Gene Alias:
MYADM, myeloid associated differentiation marker, myeloid upregulated protein, myeloid up-regulated protein, myeloid-associated differentiation marker, Protein SB135, SB135, UNQ553/PRO1110

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
91663

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
2.02 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
Q96S97

Gene Symbols:
MYADM

Immunogen:
Recombinant Human Myeloid-associated differentiation marker protein (1-40AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

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FEPA5144101

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Antigen:
Prohibitin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PHB

Gene Alias:
BAP 32, Bap32, B-cell receptor-associated protein 32, epididymis luminal protein 215, epididymis secretory sperm binding protein Li 54e, fa18f07, fb09f05, HEL-215, HEL-S-54e, OTTHUMP00000165765, OTTHUMP00000165766, OTTHUMP00000220103, OTTHUMP00000220170, OTTHUMP00000220171, PHB, phb protein, PHB1, Prohibitin, sr:nyz128, wu:fa18f07, wu:fb09f05

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5245

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
3.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P35232

Gene Symbols:
PHB

Immunogen:
Recombinant Human Prohibitin protein (1-272AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid