FEPA5144122

Mesothelin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144122-Each-of-1 In Stock ₹ 30,544.92

FEPA5144122 - Each of 1

₹ 30,544.92

In Stock

Quantity

1

Base Price: ₹ 30,544.92

GST (18%): ₹ 5,498.086

Total Price: ₹ 36,043.006

Antigen

Mesothelin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MSLN

Gene Alias

CAK1, CAK1 antigen, megakaryocyte potentiating factor, Megakaryocyte-potentiating factor, Mes, Mesothelin, Mesothelin, cleaved form, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor, SMR, SMRP, soluble MPF mesothelin related protein

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

10232

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration

3.5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.

Q13421

Gene Symbols

MSLN

Immunogen

Recombinant Human Mesothelin protein (37-598AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Originally identified as a differentiation antigen of mesotheliomas, ovarian cystadenocarcinomas, and pancreatic adenocarcinomas, Mesothelin is a glycosylphosphatidylinositol (GPI)-anchored, cell-surface glycoprotein predominantly secreted by cells of the mesothelium
  • Although Mesothelin is expressed at restricted levels by normal mesothelial cells of the pleural,pericardial, and peritoneal membranes, aberrant expression has been documented in the aforementioned cancers, as well as in endometriod uterine adenocarcinomas and squamous cell carcinomas of the esophagus, stomach, lung, and cervix
  • Proteolytic cleavage of Mesothelin yields a soluble, polypeptide fragment designated megakaryocyte potentiating factor (MPF) based on its ability to stimulate megakaryocyte colony-forming activity of murine interleukin-3 in murine bone marrow cell cultures
  • Originally isolated from the HPC-Y5 pancreatic cell line, MPF has been suggested to play a role in the proliferation and differentiation of megakaryoctyes, and the regulation of resultant platelet production
  • While the biological functions of both Mesothelin and MPF remain speculative, high-levels of expression in cancerous tissues compared to limited distribution in normal tissues strongly suggests their involvement in tumorigenesis
  • Both have been demonstrated to promote tumor cell proliferation, migration,anchorage-independent growth, and tumor progression; demonstrating their involvement in heterotypic cell adhesion and the metastatic spread of cancer.

Compare Similar Items

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Img

Thermo Scientific

FEPA5144122

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Antigen:
Mesothelin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSLN

Gene Alias:
CAK1, CAK1 antigen, megakaryocyte potentiating factor, Megakaryocyte-potentiating factor, Mes, Mesothelin, Mesothelin, cleaved form, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor, SMR, SMRP, soluble MPF mesothelin related protein

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10232

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
Q13421

Gene Symbols:
MSLN

Immunogen:
Recombinant Human Mesothelin protein (37-598AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144125

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Antigen:
MT1X

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MT1X

Gene Alias:
metallothionein 1X, metallothionein-1X, Metallothionein-IX, MT1, MT-1l, MT1X, MT-1X, MT-IX, testicular tissue protein Li 124

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4501

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
2 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P80297

Gene Symbols:
MT1X

Immunogen:
Recombinant Human Metallothionein-1X protein (1-59AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144127

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Antigen:
Complement C4b

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C4B

Gene Alias:
Acidic complement C4, Basic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, c4 complement, C4A, C4a anaphylatoxin, C4A13, C4A91, C4B, C4B_2, C4B1, C4B12, C4B2, C4B3, C4B5, C4b-A, C4b-B, C4BD, C4d-A, C4d-B, C4F, CH, Chido form of C4, CO4, Complement C4 beta chain, Complement C4 gamma chain, Complement C4-A, Complement C4-A alpha chain, Complement C4-B, Complement C4-B alpha chain, complement C4B1a, complement C4-B-like, complement component 4B (Chido blood group), complement component 4B (Chido blood group), copy 2, CPAMD2, CPAMD3, DADB-112B14.11, FLJ60561, MGC164979

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100293534, 721

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P0C0L5

Gene Symbols:
C4B, C4B_2

Immunogen:
Recombinant Human Complement C4-B protein (1454-1744AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144128

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Antigen:
IFNAG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNAG

Gene Alias:
IFNA7

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100329206

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P49877

Gene Symbols:
IFNAG

Immunogen:
Recombinant Bovine Interferon alpha-G protein (24-189AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine

Form:
Liquid