FEPA5144208
AES Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEPA5144208-Each-of-1 | In Stock | ₹ 30,544.92 |
FEPA5144208 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,544.92
GST (18%): ₹ 5,498.086
Total Price: ₹ 36,043.006
Antigen
AES
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TLE5
Gene Alias
Aes, AES-1, AES-2, AL024115, Amino enhancer of split, amino-terminal enhancer of split, Esp1, gp130-associated protein GAM, Grg, Grg5, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, related to Drosophila groucho, R-esp1, TLE family member 5, TLE family member 5, transcriptional modulator, TLE family member 5, amino-terminal enhancer of split, TLE5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
166
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Applications
ELISA, Immunohistochemistry (Paraffin)
Concentration
4.235 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q08117
Gene Symbols
AES, TLE5
Immunogen
Recombinant Human Amino-terminal enhancer of split protein (1-264AA)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Description
- Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
- Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment
- Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
- AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis
- It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family
- Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.
Compare Similar Items
Show Difference
Antigen: AES
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLE5
Gene Alias: Aes, AES-1, AES-2, AL024115, Amino enhancer of split, amino-terminal enhancer of split, Esp1, gp130-associated protein GAM, Grg, Grg5, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, related to Drosophila groucho, R-esp1, TLE family member 5, TLE family member 5, transcriptional modulator, TLE family member 5, amino-terminal enhancer of split, TLE5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 166
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 4.235 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q08117
Gene Symbols: AES, TLE5
Immunogen: Recombinant Human Amino-terminal enhancer of split protein (1-264AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
AES
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TLE5
Gene Alias:
Aes, AES-1, AES-2, AL024115, Amino enhancer of split, amino-terminal enhancer of split, Esp1, gp130-associated protein GAM, Grg, Grg5, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, related to Drosophila groucho, R-esp1, TLE family member 5, TLE family member 5, transcriptional modulator, TLE family member 5, amino-terminal enhancer of split, TLE5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
166
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
4.235 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q08117
Gene Symbols:
AES, TLE5
Immunogen:
Recombinant Human Amino-terminal enhancer of split protein (1-264AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: NMT2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NMT2
Gene Alias: A930001K02Rik, AI605445, AU044698, fb40e03, Glycylpeptide N-tetradecanoyltransferase 2, glycylpeptide N-tetradecanoyltransferase 2 variant 3, glycylpeptide N-tetradecanoyltransferase 2 variant 4, hNMT-2, myristoyl-CoA:protein N-myristoyltransferase 2, NMT 2, Nmt2, NMT2 protein, N-myristoyltransferase 2, peptide N-myristoyltransferase 2, Type II N-myristoyltransferase, wu:fb40e03
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9397
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration: 2.7 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O60551
Gene Symbols: NMT2
Immunogen: Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 protein (1-120AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
NMT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NMT2
Gene Alias:
A930001K02Rik, AI605445, AU044698, fb40e03, Glycylpeptide N-tetradecanoyltransferase 2, glycylpeptide N-tetradecanoyltransferase 2 variant 3, glycylpeptide N-tetradecanoyltransferase 2 variant 4, hNMT-2, myristoyl-CoA:protein N-myristoyltransferase 2, NMT 2, Nmt2, NMT2 protein, N-myristoyltransferase 2, peptide N-myristoyltransferase 2, Type II N-myristoyltransferase, wu:fb40e03
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9397
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration:
2.7 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O60551
Gene Symbols:
NMT2
Immunogen:
Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 protein (1-120AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: RAC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RAC3
Gene Alias: OTTMUSP00000004488, p21 Rac3, p21-Rac3, Rac1B, RAC3, RAC3_HUMAN, RAS related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 3, Ras-related C3 botulinum toxin substrate 3, Rho family small GTP binding protein Rac3, RP23-84C12.18
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5881
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 0.68 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P60763
Gene Symbols: RAC3
Immunogen: Recombinant Human Ras-related C3 botulinum toxin substrate 3 protein (1-192AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
RAC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RAC3
Gene Alias:
OTTMUSP00000004488, p21 Rac3, p21-Rac3, Rac1B, RAC3, RAC3_HUMAN, RAS related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 3, Ras-related C3 botulinum toxin substrate 3, Rho family small GTP binding protein Rac3, RP23-84C12.18
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5881
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
0.68 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P60763
Gene Symbols:
RAC3
Immunogen:
Recombinant Human Ras-related C3 botulinum toxin substrate 3 protein (1-192AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: DCTN6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DCTN6
Gene Alias: AU044699, Dctn6, dynactin 6, dynactin subunit 6, Dynactin subunit p27, novel RGD-containing protein, p27, p27 dynactin subunit, protein WS-3, RGD containing protein, WS3, WS-3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10671, 22428, 290798
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 3.03 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O00399, Q9WUB4
Gene Symbols: DCTN6
Immunogen: Recombinant Human Dynactin subunit 6 protein (1-190AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
DCTN6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DCTN6
Gene Alias:
AU044699, Dctn6, dynactin 6, dynactin subunit 6, Dynactin subunit p27, novel RGD-containing protein, p27, p27 dynactin subunit, protein WS-3, RGD containing protein, WS3, WS-3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10671, 22428, 290798
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
3.03 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O00399, Q9WUB4
Gene Symbols:
DCTN6
Immunogen:
Recombinant Human Dynactin subunit 6 protein (1-190AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid