FEPA5144235

TALK-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144235-Each-of-1 In Stock ₹ 30,544.92

FEPA5144235 - Each of 1

₹ 30,544.92

In Stock

Quantity

1

Base Price: ₹ 30,544.92

GST (18%): ₹ 5,498.086

Total Price: ₹ 36,043.006

Antigen

TALK-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNK16

Gene Alias

2P domain potassium channel Talk-1, 4731413G05Rik, K2p16.1, KCNK16, pancreatic potassium channel Talk-1, potassium channel subfamily K member 16, potassium channel, subfamily K, member 16, potassium channel, two pore domain subfamily K, member 16, potassium two pore domain channel subfamily K member 16, TALK1, TALK-1, TWIK-related alkaline pH-activated K(+) channel 1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

83795

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Immunohistochemistry (Paraffin)

Concentration

3.5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.

Q96T55

Gene Symbols

KCNK16

Immunogen

Recombinant Human Potassium channel subfamily K member 16 protein (259-309AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Description The KCNK16 gene encodes the TALK-1 channel, an abundant K+ channel transcript found in mouse and in human Beta-cells
  • There are four human TALK-1 transcript variants, including two that form functional K+ channels (TALK-1a (transcript variant 2) and TALK1-b (transcript variant 3)
  • The TALK-1 structure includes 4 transmembrane domains, 2 extracellular loops, and intracellular N- and C-termini
  • The C-terminal tail of TALK-1 is a critical component that influences the magnitude of TALK-1 channel activation, while the N-terminus is important for protein interaction
  • TALK-1, two-pore domain K+ (K2p 16.1) channel is responsible for modulating glucose stimulated insulin secretion that relies on Beta-cell CA2+ influx
  • The channel produces outwardly rectifying, non-inactivating K+ currents, which are enhanced by elevations in extracellular pH
  • TALK-1 is thus pH-sensitive, with increased activity under alkaline conditions
  • In addition, it can be activated by singlet oxygen and nitric oxide.

Compare Similar Items

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Img

Thermo Scientific

FEPA5144235

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Antigen:
TALK-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNK16

Gene Alias:
2P domain potassium channel Talk-1, 4731413G05Rik, K2p16.1, KCNK16, pancreatic potassium channel Talk-1, potassium channel subfamily K member 16, potassium channel, subfamily K, member 16, potassium channel, two pore domain subfamily K, member 16, potassium two pore domain channel subfamily K member 16, TALK1, TALK-1, TWIK-related alkaline pH-activated K(+) channel 1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
83795

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
Q96T55

Gene Symbols:
KCNK16

Immunogen:
Recombinant Human Potassium channel subfamily K member 16 protein (259-309AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144238

--


Antigen:
PRDX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRDX3

Gene Alias:
antioxidant protein, antioxidant protein 1, anti-oxidant protein 1, Aop1, AOP-1, AW822249, D0Tohi1, Ef2l, HBC189, Mer5, mitochondrial thioredoxin dependent peroxide reductase, mitochondrial Trx dependent peroxide reductase, perioredoxin-3, peroxiredoxin 3, peroxiredoxin III, Peroxiredoxin-3, Prdx3, PRO1748, Protein MER5, Protein MER5 homolog, Prx, Prx 3, PRx III, Prx3, PRX-3, Prx-III, SP22, SP-22, TDXM, thioredoxin-dependent peroxide reductase, mitochondrial

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10935, 11757

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P20108, P30048

Gene Symbols:
PRDX3

Immunogen:
Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein (63-256AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Thermo Scientific

FEPA5144247

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Antigen:
LIPG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LIPG

Gene Alias:
3110013K01Rik, EDL, EL, endothelial cell-derived lipase, Endothelial lipase, endothelial-derived lipase, lipase, lipase G, lipase G, endothelial type, lipase, endothelial, LIPG, lipoprotein lipase H, lipose, endothelial, mEDL, PL, PRO719, UNQ387/PRO719

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9388

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
Q9Y5X9

Gene Symbols:
LIPG

Immunogen:
Recombinant Human Endothelial lipase protein (360-500AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144250

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Antigen:
TGF beta-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tgfb1

Gene Alias:
CED, cytokine, DPD1, LAP, Latency-associated peptide, prepro-transforming growth factor beta-1, regulatory protein, TGF b, TGF b 1, TGF beta, tgf beta 1, tgf beta1, TGF beta-1, TGF beta-1 protein, TGF β, TGF β, 1, TGF β1, Tgfb, TGFB1, TGF-B1, Tgfb-1, TGFbeta, TGF-beta 1, TGF-beta 1 protein, TGFbeta1, TGF-beta1, TGF-beta-1, TGFβ1, Transforming growth factor, transforming growth factor b1, transforming growth factor beta, transforming growth factor beta 1, transforming growth factor beta-1, Transforming growth factor beta-1 proprotein, transforming growth factor beta-1 proprotein, transforming growth factor beta-1, transforming growth factor β1, transforming growth factor, beta 1, transforming growth factor, beta 1 (Camurati-Engelmann disease), transforming growth factor, beta-1, transforming growth factor-beta 1, transforming growth factor-beta I, transforming growth factor-beta-1, transforming growth factor-beta-1 precursor, unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21803, 7040

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P01137, P04202

Gene Symbols:
Tgfb1

Immunogen:
Recombinant Mouse Transforming growth factor beta-1 protein (30-278AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid