FEPA5144504

E3L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144504-Each-of-1 In Stock ₹ 30,544.92

FEPA5144504 - Each of 1

₹ 30,544.92

In Stock

Quantity

1

Base Price: ₹ 30,544.92

GST (18%): ₹ 5,498.086

Total Price: ₹ 36,043.006

Antigen

E3L

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

Protein E3

Immunogen

Recombinant Vaccinia virus Protein E3 (E3L) (1-190AA)

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Western Blot

Concentration

2.5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Target Species

Virus

Form

Liquid

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Description

  • RNA-binding protein that plays a role in the inhibition of multiple cellular antiviral responses activated by double-stranded RNA (dsRNA), such as inhibition of PKR activation, necroptosis, and IFN-mediated antiviral activities
  • Recognizes and binds Z-RNA structures via its Z-binding domain and dsRNA via its DRBM domain: RNA-binding activity is required to escape host ZBP1-dependent necroptosis
  • Mechanistically, the Z-binding domain binds Z-RNAs that are produced during vaccinia virus infection, thereby competing with Z-RNA detection by host ZBP1, suppressing ZBP1-dependent necroptosis
  • Acts as a key inhibitor of the interferon response by blocking the phosphorylation and subsequent activation of IRF3 and IRF7 kinases that are required for interferon-alpha gene expression
  • Inhibits NF-kappa-B activation and the ubiquitin-like protein ISG15, which is an early antiviral protein
  • The binding with host ISG15 subsequently blocks host ISGylation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEPA5144504

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Antigen:
E3L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Protein E3

Immunogen:
Recombinant Vaccinia virus Protein E3 (E3L) (1-190AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Western Blot

Concentration:
2.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Virus

Form:
Liquid

Img

Thermo Scientific

FEPA5144506

--


Antigen:
epiA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
epiA, Lantibiotic epidermin

Immunogen:
Recombinant Staphylococcus epidermidis Lantibiotic epidermin (epiA) (31-52AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Western Blot

Concentration:
2.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Bacteria

Form:
Liquid

Img

Thermo Scientific

FEPA5144508

--


Antigen:
bamA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
yaeT, yzzN, yzzY

Immunogen:
Recombinant Escherichia coli Outer membrane protein assembly factor BamA (BamA), partial (175-424AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Western Blot

Concentration:
2.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Bacteria

Form:
Liquid

Img

Thermo Scientific

FEPA5144509

--


Antigen:
csgD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Probable csgAB operon

Immunogen:
Recombinant Salmonella typhimurium (strain LT2/SGSC1412/ATCC 700720) csgD protein (1-216aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Western Blot

Concentration:
2.559 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Bacteria

Form:
Liquid