FEPA5145239

ATF6 Polyclonal Antibody, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5145239-Each-of-1 In Stock ₹ 31,400.52

FEPA5145239 - Each of 1

₹ 31,400.52

In Stock

Quantity

1

Base Price: ₹ 31,400.52

GST (18%): ₹ 5,652.094

Total Price: ₹ 37,052.614

Antigen

ATF6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6

Gene Alias

9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12915, 1388, 226641, 22926

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

F6VAN0, O35451, P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

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Description

  • ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

Compare Similar Items

Show Difference

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Fischer Scientific

FEPA5145239

--


Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12915, 1388, 226641, 22926

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
F6VAN0, O35451, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Fischer Scientific

FEPA5145240

--


Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12915, 1388, 226641, 22926

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
F6VAN0, O35451, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Fischer Scientific

FEPA5145241

--


Antigen:
GPX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gpx3

Gene Alias:
AA960521, EGPx, extracellular glutathione peroxidase, extracellular GPx, glutathione peroxidase 3, glutathione peroxidase 3 (plasma), GPx, Gpx3, GPx-3, Gpxp, GPx-P, GSHPx-3, GSHPx-P, plasma form, plasma glutathione peroxidase, plasma GPx

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14778, 64317

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P23764, P46412

Gene Symbols:
Gpx3

Immunogen:
Recombinant Mouse GPX3 protein, Arg3-Tyr72 (Accession #P46412)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Liquid

Img

Fischer Scientific

FEPA5145242

--


Antigen:
GPX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gpx3

Gene Alias:
AA960521, EGPx, extracellular glutathione peroxidase, extracellular GPx, glutathione peroxidase 3, glutathione peroxidase 3 (plasma), GPx, Gpx3, GPx-3, Gpxp, GPx-P, GSHPx-3, GSHPx-P, plasma form, plasma glutathione peroxidase, plasma GPx

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14778, 64317

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P23764, P46412

Gene Symbols:
Gpx3

Immunogen:
Recombinant Mouse GPX3 protein, Arg3-Tyr72 (Accession #P46412)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Liquid