FEPA5145265

Histone H2A.X Polyclonal Antibody, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5145265-Each-of-1 In Stock ₹ 37,202.00

FEPA5145265 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

Histone H2A.X

Classification

Polyclonal

Conjugate

Unconjugated

Gene

H2AX

Gene Alias

AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

15270, 3014

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P16104, P27661

Gene Symbols

H2AX

Immunogen

Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

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Description

  • Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
  • In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
  • The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
  • The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
  • Structurally, H2A.x contains 143 amino acid residues
  • Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
  • There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
  • The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
  • Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
  • Histone H2A.x contributes to histone-formation and therefore the structure of DNA
  • Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.

Compare Similar Items

Show Difference

Img

Fischer Scientific

FEPA5145265

--


Antigen:
Histone H2A.X

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AX

Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 3014

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P16104, P27661

Gene Symbols:
H2AX

Immunogen:
Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Fischer Scientific

FEPA5145266

--


Antigen:
Histone H2A.X

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AX

Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 3014

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P16104, P27661

Gene Symbols:
H2AX

Immunogen:
Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Fischer Scientific

FEPA5145267

--


Antigen:
Apolipoprotein A5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOA5

Gene Alias:
1300007O05Rik, APOA5, Apoav, apo-AV, apoA-V, apolipoprotein A5, apolipoprotein AV, Apolipoprotein A-V, apolipoprotein A-V precursor variant 3, apolipoprotein A-V, apolipoprotein A5, FLJ97995, MGC126836, MGC126838, Rap3, Regeneration-associated protein 3, UNQ411/PRO773

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
140638, 66113

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q8C7G5, Q9QUH3

Gene Symbols:
APOA5

Immunogen:
Recombinant Mouse APOA5 protein, Arg21-Pro210 (Accession #Q8C7G5)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Liquid

Img

Fischer Scientific

FEPA5145268

--


Antigen:
Apolipoprotein A5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOA5

Gene Alias:
1300007O05Rik, APOA5, Apoav, apo-AV, apoA-V, apolipoprotein A5, apolipoprotein AV, Apolipoprotein A-V, apolipoprotein A-V precursor variant 3, apolipoprotein A-V, apolipoprotein A5, FLJ97995, MGC126836, MGC126838, Rap3, Regeneration-associated protein 3, UNQ411/PRO773

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
140638, 66113

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q8C7G5, Q9QUH3

Gene Symbols:
APOA5

Immunogen:
Recombinant Mouse APOA5 protein, Arg21-Pro210 (Accession #Q8C7G5)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Liquid