FEPA5145265
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEPA5145265-Each-of-1 | In Stock | ₹ 35,764.08 |
FEPA5145265 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Liquid
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
Compare Similar Items
Show Difference
Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Recombinant Human H2AFX protein, Ser2-Tyr143 (Accession #P16104)
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Antigen: Apolipoprotein A5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOA5
Gene Alias: 1300007O05Rik, APOA5, Apoav, apo-AV, apoA-V, apolipoprotein A5, apolipoprotein AV, Apolipoprotein A-V, apolipoprotein A-V precursor variant 3, apolipoprotein A-V, apolipoprotein A5, FLJ97995, MGC126836, MGC126838, Rap3, Regeneration-associated protein 3, UNQ411/PRO773
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 140638, 66113
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.: Q8C7G5, Q9QUH3
Gene Symbols: APOA5
Immunogen: Recombinant Mouse APOA5 protein, Arg21-Pro210 (Accession #Q8C7G5)
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Liquid
Antigen:
Apolipoprotein A5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOA5
Gene Alias:
1300007O05Rik, APOA5, Apoav, apo-AV, apoA-V, apolipoprotein A5, apolipoprotein AV, Apolipoprotein A-V, apolipoprotein A-V precursor variant 3, apolipoprotein A-V, apolipoprotein A5, FLJ97995, MGC126836, MGC126838, Rap3, Regeneration-associated protein 3, UNQ411/PRO773
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
140638, 66113
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.:
Q8C7G5, Q9QUH3
Gene Symbols:
APOA5
Immunogen:
Recombinant Mouse APOA5 protein, Arg21-Pro210 (Accession #Q8C7G5)
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Liquid
Antigen: Apolipoprotein A5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOA5
Gene Alias: 1300007O05Rik, APOA5, Apoav, apo-AV, apoA-V, apolipoprotein A5, apolipoprotein AV, Apolipoprotein A-V, apolipoprotein A-V precursor variant 3, apolipoprotein A-V, apolipoprotein A5, FLJ97995, MGC126836, MGC126838, Rap3, Regeneration-associated protein 3, UNQ411/PRO773
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 140638, 66113
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.: Q8C7G5, Q9QUH3
Gene Symbols: APOA5
Immunogen: Recombinant Mouse APOA5 protein, Arg21-Pro210 (Accession #Q8C7G5)
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Liquid
Antigen:
Apolipoprotein A5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOA5
Gene Alias:
1300007O05Rik, APOA5, Apoav, apo-AV, apoA-V, apolipoprotein A5, apolipoprotein AV, Apolipoprotein A-V, apolipoprotein A-V precursor variant 3, apolipoprotein A-V, apolipoprotein A5, FLJ97995, MGC126836, MGC126838, Rap3, Regeneration-associated protein 3, UNQ411/PRO773
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
140638, 66113
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.:
Q8C7G5, Q9QUH3
Gene Symbols:
APOA5
Immunogen:
Recombinant Mouse APOA5 protein, Arg21-Pro210 (Accession #Q8C7G5)
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Liquid