FERMA548474

CXCR3 Monoclonal Antibody (5C10B3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548474-Each-of-1 In Stock ₹ 41,881.62

FERMA548474 - Each of 1

₹ 41,881.62

In Stock

Quantity

1

Base Price: ₹ 41,881.62

GST (18%): ₹ 7,538.692

Total Price: ₹ 49,420.312

Antigen

CXCR3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P49682

Gene Symbols

CXCR3

Immunogen

Purified recombinant fragment of human CD183 (AA: extra mix) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

5C10B3

Conjugate

Unconjugated

Gene

CXCR3

Gene Alias

an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

2833

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant)
  • IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first two of four highly conserved Cys residues
  • Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration
  • Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to this protein
  • Signal transduction has not been further analyzed but may include the same enzymes that were identified in the signaling cascade induced by other chemokine receptors
  • As a consequence of chemokine-induced cellular desensitization (phosphorylation-dependent receptor internalization), cellular responses are typically rapid and short in duration
  • Cellular responsiveness is restored after dephosphorylation of intracellular receptors and subsequent recycling to the cell surface
  • This gene is prominently expressed in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues
  • In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that this gene and its chemokines participate in the recruitment of inflammatory cells
  • Therefore, this protein is a target for the development of small molecular weight antagonists, which may be used in the treatment of diverse inflammatory diseases
  • Multiple transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

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Thermo Scientific

FERMA548474

--


Antigen:
CXCR3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P49682

Gene Symbols:
CXCR3

Immunogen:
Purified recombinant fragment of human CD183 (AA: extra mix) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
5C10B3

Conjugate:
Unconjugated

Gene:
CXCR3

Gene Alias:
an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2833

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

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FERMA548475

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Antigen:
GPR15

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P49685

Gene Symbols:
GPR15

Immunogen:
Purified recombinant fragment of human GPR15 (AA: extra mix) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2C2A8

Conjugate:
Unconjugated

Gene:
GPR15

Gene Alias:
4933439K08Rik; BoB; brother of Bonzo; G protein-coupled receptor 15; GPR15; Gpr-15; G-protein coupled receptor 15; MGC126828; MGC126830

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2838

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

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FERMA548477

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Antigen:
NMDAR2A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q12879

Gene Symbols:
Grin2a

Immunogen:
Purified recombinant fragment of human GRIN2A (AA: extra 23-165) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3G10F9

Conjugate:
Unconjugated

Gene:
Grin2a

Gene Alias:
EPND; FESD; GluN2A; GluRepsilon1; glutamate [NMDA] receptor subunit epsilon-1; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor; glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Grin2a; hNR2A; LKS; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2903

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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FERMA548479

--


Antigen:
mGluR2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q14416

Gene Symbols:
GRM2

Immunogen:
Purified recombinant fragment of human GRM2 (AA: extra 414-558) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
4A10B9

Conjugate:
Unconjugated

Gene:
GRM2

Gene Alias:
4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; GLUR2; glutamate metabotropic receptor 2; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; GPRC1B; Grm2; M mGlu2; Metabotropic; Metabotropic glutamate receptor 2; mGlu2; MGLUR2; mGluR7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2912

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1