FERMA548553

HRX Monoclonal Antibody (7E1D10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548553-Each-of-1 In Stock ₹ 41,881.62

FERMA548553 - Each of 1

₹ 41,881.62

In Stock

Quantity

1

Base Price: ₹ 41,881.62

GST (18%): ₹ 7,538.692

Total Price: ₹ 49,420.312

Antigen

HRX

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q03164

Gene Symbols

KMT2A

Immunogen

Purified recombinant fragment of human KMT2A (AA: 150-400) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

7E1D10

Conjugate

Unconjugated

Gene

KMT2A

Gene Alias

6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4297

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
  • It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
  • In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
  • KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
  • It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
  • Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.

Compare Similar Items

Show Difference

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Thermo Scientific

FERMA548553

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Antigen:
HRX

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q03164

Gene Symbols:
KMT2A

Immunogen:
Purified recombinant fragment of human KMT2A (AA: 150-400) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7E1D10

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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FERMA548555

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Antigen:
CD206 (MMR)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P22897

Gene Symbols:
Mrc1

Immunogen:
Purified recombinant fragment of human CD206 (AA: extra(19-218)) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
4B11C12

Conjugate:
Unconjugated

Gene:
Mrc1

Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4360

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

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FERMA548557

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Antigen:
HEF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q14511

Gene Symbols:
NEDD9

Immunogen:
Purified recombinant fragment of human NEDD9 (AA: 82-398) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3F7A9

Conjugate:
Unconjugated

Gene:
NEDD9

Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4739

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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FERMA548558

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Antigen:
NeuroD1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q13562

Gene Symbols:
NEUROD1

Immunogen:
Purified recombinant fragment of human Neurod (AA: 26-91) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
8C4H4

Conjugate:
Unconjugated

Gene:
NEUROD1

Gene Alias:
Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; beta-cell E-box transcriptional activator 2; BHF1; BHF-1; bHLHa3; Class A basic helix-loop-helix protein 3; MODY6; neuro d1; Neurod; Neurod1; neurogenic differentiation 1; neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4760

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1