FERMA548574

PLCG2 Monoclonal Antibody (1E10C11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548574-Each-of-1 In Stock ₹ 41,881.62

FERMA548574 - Each of 1

₹ 41,881.62

In Stock

Quantity

1

Base Price: ₹ 41,881.62

GST (18%): ₹ 7,538.692

Total Price: ₹ 49,420.312

Antigen

PLCG2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P16885

Gene Symbols

Plcg2

Immunogen

Purified recombinant fragment of human PLCG2 (AA: 826-985) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

1E10C11

Conjugate

Unconjugated

Gene

Plcg2

Gene Alias

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5336

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate
  • There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLCe
  • PLC delta exists as four different isoforms
  • PLC delta1, a calcium signal amplifier, is activated by an atypical GTP-binding protein
  • In addition, PLC delta1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and alpha1B-adrenoreceptor signaling
  • Mouse PLC delta1 is highly expressed in brain, heart, lung and testis
  • PLC delta is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD
  • PLC delta2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma
  • When PLC delta2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation
  • Thus, PLC delta2 expression may be a possible marker of gastric malignant transformation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA548574

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Antigen:
PLCG2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P16885

Gene Symbols:
Plcg2

Immunogen:
Purified recombinant fragment of human PLCG2 (AA: 826-985) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
1E10C11

Conjugate:
Unconjugated

Gene:
Plcg2

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5336

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

FERMA548575

--


Antigen:
PMS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P54278

Gene Symbols:
PMS2

Immunogen:
Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
8E4G11

Conjugate:
Unconjugated

Gene:
PMS2

Gene Alias:
AW555130; DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 postmeiotic segregation increased 2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); PMS2CL; PMSL2; postmeiotic segregation increased 2; postmeiotic segregation increased 2 (S. cerevisiae); postmeiotic segregation increased 2 nirs variant 6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5395

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

FERMA548576

--


Antigen:
PMS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P54278, P54279

Gene Symbols:
PMS2

Immunogen:
Purified recombinant fragment of human PMS2 (AA: (431-580)) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
6G12E1

Conjugate:
Unconjugated

Gene:
PMS2

Gene Alias:
AW555130; DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 postmeiotic segregation increased 2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); PMS2CL; PMSL2; postmeiotic segregation increased 2; postmeiotic segregation increased 2 (S. cerevisiae); postmeiotic segregation increased 2 nirs variant 6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18861, 5395

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

FERMA548577

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Antigen:
AMPK alpha 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P54646

Gene Symbols:
PRKAA2

Immunogen:
Purified recombinant fragment of human PRKAA2 (AA: 453-552) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
8E11H5

Conjugate:
Unconjugated

Gene:
PRKAA2

Gene Alias:
2310008I11Rik; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; A830082D05; ACACA kinase; Acetyl-CoA carboxylase kinase; AMP-activated protein kinase; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMP-activated protein kinase alpha-2 variant B; AMPK; AMPK alpha 2; AMPK alpha-2 chain; AMPK subunit alpha-2; AMPK2; AMPKa2; AMPKalpha2; AMPK-alpha-2 chain; EC 2.7.11.1; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; PRKAA; Prkaa2; protein kinase AMP-activated catalytic subunit alpha 2; protein kinase, AMP-activated, alpha 2 catalytic subunit

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5563

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1